| Date | Res | Opp | OW-OL | ||
| 11/13/2009 | W 88-68 | Idaho St | 5-23 | ||
| 11/15/2009 | W 72-50 | Chicago St | 6-21 | ||
| 11/17/2009 | W 90-70 | @ | Drake | 14-18 | |
| 11/22/2009 | W 96-55 | Miss Valley St | 9-22 | Chicago Challenge | |
| 11/24/2009 | W 84-53 | Tennessee St | 10-22 | Chicago Challenge | |
| 11/27/2009 | W 65-54 | vs | Saint Louis | 19-10 | Chicago Challenge |
| 11/28/2009 | L 65-67 | vs | Northwestern | 19-12 | Chicago Challenge |
| 12/2/2009 | L 60-63 | Northern Iowa | 26-4 | ||
| 12/5/2009 | L 63-82 | @ | California | 22-10 | |
| 12/11/2009 | W 81-71 | Iowa | 10-21 | ||
| 12/20/2009 | W 87-68 | Bradley | 16-13 | ||
| 12/22/2009 | W 83-25 | North Dakota | 6-20 | ||
| 1/3/2010 | W 82-75 2 OT | Houston | 18-14 | ||
| 1/6/2010 | L 65-86 | vs | Duke | 28-5 | |
| 1/9/2010 | W 73-71 | North Dakota St | 10-17 | ||
| 1/13/2010 | L 83-90 | Texas | 22-9 | ||
| 1/16/2010 | W 56-53 | @ | Nebraska | 15-16 | |
| 1/20/2010 | L 71-78 | @ | Texas Tech | 17-14 | |
| 1/23/2010 | L 61-84 | Kansas | 30-2 | ||
| 1/27/2010 | L 84-89 | @ | Oklahoma | 13-17 | |
| 1/30/2010 | W 64-63 | Colorado | 11-16 | ||
| 2/3/2010 | L 63-84 | @ | Baylor | 22-8 | |
| 2/6/2010 | L 75-79 | Kansas St | 24-6 | ||
| 2/10/2010 | L 56-65 | @ | Missouri | 21-9 | |
| 2/13/2010 | L 59-73 | @ | Kansas | 30-2 | |
| 2/17/2010 | L 64-69 | Oklahoma St | 20-11 | ||
| 2/20/2010 | L 56-60 | Texas A&M | 21-9 | ||
| 2/24/2010 | W 78-74 | Nebraska | 15-16 | ||
| 2/27/2010 | L 72-75 | @ | Colorado | 11-16 | |
| 3/2/2010 | L 67-69 OT | Missouri | 21-9 | ||
| 3/6/2010 | W 85-82 | Kansas St | 24-6 | ||
| 3/10/2010 | L 75-82 | vs | Texas | 22-9 | Big 12 |
| 15-17 | 434-349 |