| Date | Res | Opp | OW-OL | ||
| 11/15/2009 | W 89-42 | UC Irvine | 12-17 | ||
| 11/18/2009 | W 73-41 | Western Carolina | 18-11 | CBE Classic | |
| 11/23/2009 | W 85-60 | vs | Iowa | 10-21 | CBE Classic |
| 11/24/2009 | W 78-62 | vs | Pittsburgh | 24-7 | CBE Classic |
| 11/29/2009 | W 77-59 | @ | Rice | 7-22 | |
| 12/3/2009 | W 69-50 | Southern California | 17-12 | ||
| 12/7/2009 | W 107-74 | Long Beach | 15-15 | ||
| 12/12/2009 | W 87-54 | Texas St | 11-15 | ||
| 12/15/2009 | W 104-42 | UT Pan American | 5-27 | ||
| 12/19/2009 | W 103-90 | vs | North Carolina | 16-14 | |
| 12/22/2009 | W 79-68 | Michigan St | 24-8 | ||
| 12/29/2009 | W 95-63 | Gardner Webb | 6-20 | ||
| 1/2/2010 | W 76-70 | Texas A&M CC | 14-14 | ||
| 1/5/2010 | W 96-85 | @ | Arkansas | 15-16 | |
| 1/9/2010 | W 103-86 | Colorado | 12-16 | ||
| 1/13/2010 | W 90-83 | @ | Iowa State | 15-15 | |
| 1/16/2010 | W 72-67 OT | Texas A&M | 21-8 | ||
| 1/18/2010 | L 62-71 | @ | Kansas St | 24-7 | |
| 1/23/2010 | L 74-88 | @ | Connecticut | 17-14 | |
| 1/27/2010 | W 95-83 | Texas Tech | 18-12 | ||
| 1/30/2010 | L 77-80 OT | Baylor | 21-8 | ||
| 2/1/2010 | W 72-60 | @ | Oklahoma St | 21-9 | |
| 2/6/2010 | L 71-80 | @ | Oklahoma | 12-16 | |
| 2/8/2010 | L 68-80 | Kansas | 31-2 | ||
| 2/13/2010 | W 91-51 | Nebraska | 15-17 | ||
| 2/17/2010 | L 77-82 | @ | Missouri | 22-9 | |
| 2/20/2010 | W 71-67 | @ | Texas Tech | 18-12 | |
| 2/24/2010 | W 69-59 | Oklahoma St | 21-9 | ||
| 2/27/2010 | L 58-74 | @ | Texas A&M | 21-8 | |
| 3/1/2010 | W 87-76 | Oklahoma | 12-16 | ||
| 3/6/2010 | L 71-80 | @ | Oklahoma | 12-16 | |
| 3/10/2010 | W 82-75 | vs | Iowa State | 15-15 | Big 12 |
| 3/11/2010 | L 67-86 | vs | Baylor | 21-8 | Big 12 |
| 24-9 | 423-352 |