| Date | Res | Opp | OW-OL | ||
| 11/14/2009 | W 59-41 | SE Missouri St | 6-23 | ||
| 11/18/2009 | W 69-55 | Nebraska | 15-17 | ||
| 11/22/2009 | W 76-66 | Kennesaw St | 11-19 | Chicago Challenge | |
| 11/24/2009 | W 75-39 | Miss Valley St | 9-22 | Chicago Challenge | |
| 11/27/2009 | L 54-65 | vs | Iowa State | 14-17 | Chicago Challenge |
| 11/28/2009 | L 52-64 | vs | Notre Dame | 21-11 | Chicago Challenge |
| 12/2/2009 | L 56-64 | @ | Georgia | 14-16 | |
| 12/5/2009 | W 71-61 | Southern Illinois | 14-15 | ||
| 12/16/2009 | W 75-67 | Belmont | 20-11 | ||
| 12/19/2009 | L 63-73 | Missouri St | 20-11 | ||
| 12/22/2009 | W 61-54 | UMKC | 10-17 | ||
| 12/29/2009 | W 60-42 | Eastern Illinois | 18-10 | ||
| 1/2/2010 | L 50-59 | @ | Bowling Green | 12-17 | |
| 1/9/2010 | W 63-58 | Richmond | 25-7 | ||
| 1/13/2010 | W 79-75 2 OT | @ | Duquesne | 15-13 | |
| 1/17/2010 | L 61-63 OT | at | Charlotte | 19-12 | |
| 1/20/2010 | W 75-48 | Fordham | 2-25 | ||
| 1/27/2010 | L 62-67 OT | @ | George Washington | 15-14 | |
| 1/30/2010 | L 36-62 | @ | Richmond | 25-7 | |
| 2/3/2010 | W 67-65 | St. Bonaventure | 14-14 | ||
| 2/6/2010 | W 68-65 | @ | La Salle | 12-16 | |
| 2/9/2010 | W 56-52 | @ | Saint Joseph's | 10-19 | |
| 2/13/2010 | W 68-65 OT | Dayton | 21-10 | ||
| 2/17/2010 | W 62-57 | Rhode Island | 23-7 | ||
| 2/21/2010 | W 69-56 | @ | Massachusetts | 10-20 | |
| 2/24/2010 | L 71-73 | Xavier | 22-9 | ||
| 2/27/2010 | W 69-59 | Duquesne | 15-13 | ||
| 3/3/2010 | L 51-57 | Temple | 27-5 | ||
| 3/6/2010 | W 68-65 | @ | La Salle | 12-16 | |
| 3/12/2010 | L 47-63 | vs | Rhode Island | 23-7 | Atlantic 10 |
| 19-11 | 399-377 |