| Date | Res | Opp | OW-OL | ||
| 11/14/2009 | W 76-49 | SC Upstate | 7-22 | ||
| 11/18/2009 | L 55-69 | @ | Saint Louis | 18-11 | |
| 11/21/2009 | W 90-77 | TCU | 12-17 | ||
| 11/24/2009 | W 70-48 | UMKC | 10-17 | ||
| 11/29/2009 | W 51-48 | @ | Southern California | 17-12 | |
| 12/2/2009 | W 81-53 | UT Pan American | 5-27 | ||
| 12/6/2009 | L 61-67 | @ | Creighton | 15-15 | |
| 12/10/2009 | W 74-39 | Chicago St | 6-21 | ||
| 12/12/2009 | W 50-44 | Oregon St | 15-15 | ||
| 12/19/2009 | W 57-41 | Jackson St | 18-11 | Las Vegas Classic | |
| 12/22/2009 | W 74-70 | vs | Tulsa | 22-10 | Las Vegas Classic |
| 12/23/2009 | L 66-88 | vs | BYU | 26-6 | Las Vegas Classic |
| 12/29/2009 | W 94-61 | Southern Utah | 5-22 | ||
| 1/2/2010 | W 74-60 | UM Eastern Shore | 11-21 | ||
| 1/5/2010 | W 77-59 | SE Louisiana | 14-12 | ||
| 1/9/2010 | L 53-64 | @ | Texas A&M | 20-9 | |
| 1/13/2010 | L 72-84 | Kansas | 29-2 | ||
| 1/16/2010 | L 53-56 | Iowa State | 13-17 | ||
| 1/23/2010 | L 53-70 | @ | Missouri | 21-8 | |
| 1/27/2010 | L 60-72 | @ | Colorado | 10-17 | |
| 1/30/2010 | W 63-46 | Oklahoma | 14-16 | ||
| 2/2/2010 | L 57-76 | Kansas St | 23-7 | ||
| 2/6/2010 | L 64-75 | @ | Kansas | 29-2 | |
| 2/10/2010 | L 53-55 | Baylor | 22-8 | ||
| 2/13/2010 | L 51-91 | @ | Texas | 23-9 | |
| 2/17/2010 | L 87-91 | @ | Kansas St | 23-7 | |
| 2/20/2010 | L 59-74 | Missouri | 21-8 | ||
| 2/24/2010 | L 74-78 | @ | Iowa State | 13-17 | |
| 2/27/2010 | W 83-79 2 OT | Texas Tech | 18-13 | ||
| 3/2/2010 | L 68-81 | Colorado | 10-17 | ||
| 3/6/2010 | L 64-75 | @ | Kansas | 29-2 | |
| 3/10/2010 | W 75-60 | vs | Missouri | 21-8 | Big 12 |
| 3/11/2010 | L 64-70 | vs | Texas A&M | 20-9 | Big 12 |
| 15-18 | 394-345 |