| Date | Res | Opp | OW-OL | ||
| 11/9/2009 | W 75-70 | at | Murray St | 27-3 | Coaches vs Cancer |
| 11/11/2009 | W 95-61 | at | Detroit | 18-13 | Coaches vs Cancer |
| 11/19/2009 | L 73-95 | vs | Syracuse | 27-3 | Coaches vs Cancer |
| 11/20/2009 | L 70-76 | vs | Ohio State | 26-7 | Coaches vs Cancer |
| 11/24/2009 | W 79-47 | Jacksonville | 19-11 | ||
| 11/29/2009 | W 81-60 | Princeton | 19-7 | ||
| 12/2/2009 | L 78-86 | @ | New Mexico | 29-4 | |
| 12/5/2009 | W 82-63 | Iowa State | 15-16 | ||
| 12/9/2009 | W 79-54 | @ | Pacific | 20-10 | |
| 12/22/2009 | L 69-84 | @ | Kansas | 31-2 | |
| 12/28/2009 | W 85-51 | Utah Valley | 9-16 | Cal Tournament | |
| 12/29/2009 | W 87-66 | UC Santa Barbara | 20-8 | Cal Tournament | |
| 1/2/2010 | W 92-66 | Stanford | 14-17 | ||
| 1/6/2010 | L 75-76 OT | UCLA | 13-15 | ||
| 1/9/2010 | W 67-59 | Southern California | 16-12 | ||
| 1/14/2010 | W 93-88 | @ | Washington St | 16-12 | |
| 1/16/2010 | L 69-84 | @ | Washington | 22-8 | |
| 1/21/2010 | W 89-57 | Oregon | 15-14 | ||
| 1/23/2010 | W 65-61 | Oregon St | 14-15 | ||
| 1/28/2010 | W 78-70 | @ | Arizona St | 21-9 | |
| 1/31/2010 | L 72-76 | @ | Arizona | 14-15 | |
| 2/4/2010 | L 63-66 | @ | Southern California | 16-12 | |
| 2/6/2010 | W 72-58 | @ | UCLA | 13-15 | |
| 2/11/2010 | W 93-81 | Washington | 22-8 | ||
| 2/13/2010 | W 86-70 | Washington St | 16-12 | ||
| 2/18/2010 | L 64-80 | @ | Oregon St | 14-15 | |
| 2/20/2010 | W 64-49 | @ | Oregon | 15-14 | |
| 2/25/2010 | W 95-71 | Arizona | 14-15 | ||
| 2/27/2010 | W 62-46 | Arizona St | 21-9 | ||
| 3/6/2010 | W 72-58 | @ | UCLA | 13-15 | |
| 3/11/2010 | W 90-74 | vs | Oregon | 15-14 | Pac-10 |
| 3/12/2010 | W 85-72 | vs | UCLA | 13-15 | Pac-10 |
| 3/13/2010 | L 75-79 | vs | Washington | 22-8 | Pac-10 |
| 23-10 | 405-217 |