| Date | Res | Opp | OW-OL | ||
| 11/13/2009 | W 71-65 | @ | Denver | 19-12 | |
| 11/20/2009 | L 52-60 | vs | DePaul | 7-23 | Paradise Jam |
| 11/21/2009 | W 74-68 | vs | East Carolina | 7-20 | Paradise Jam |
| 11/23/2009 | W 81-69 | vs | Boston College | 15-16 | Paradise Jam |
| 11/28/2009 | W 52-45 | Northern Illinois | 10-20 | ||
| 12/2/2009 | W 63-60 | @ | Iowa State | 15-16 | |
| 12/8/2009 | W 67-50 | Iowa | 10-21 | ||
| 12/12/2009 | W 82-65 | Siena | 27-5 | ||
| 12/19/2009 | W 64-41 | @ | North Dakota | 6-20 | |
| 12/23/2009 | W 72-54 | Wyoming | 8-20 | ||
| 12/29/2009 | W 60-52 | @ | Creighton | 16-13 | |
| 1/1/2010 | W 65-46 | at | Evansville | 7-21 | |
| 1/3/2010 | W 84-76 | Missouri St | 21-9 | ||
| 1/6/2010 | W 61-49 | @ | Southern Illinois | 14-13 | |
| 1/9/2010 | W 59-44 | @ | Illinois St | 22-7 | |
| 1/12/2010 | W 52-50 | Bradley | 15-13 | ||
| 1/16/2010 | W 62-40 | Indiana St | 16-12 | ||
| 1/19/2010 | L 51-60 | @ | Wichita St | 22-7 | |
| 1/24/2010 | W 67-58 | @ | Indiana St | 16-12 | |
| 1/27/2010 | W 67-51 | Drake | 14-17 | ||
| 1/30/2010 | W 55-54 | @ | Missouri St | 21-9 | |
| 2/3/2010 | W 59-56 | Wichita St | 22-7 | ||
| 2/6/2010 | W 55-52 | Southern Illinois | 14-13 | ||
| 2/10/2010 | W 57-48 | @ | Drake | 14-17 | |
| 2/13/2010 | L 59-68 | @ | Bradley | 15-13 | |
| 2/16/2010 | W 70-52 | Creighton | 16-13 | ||
| 2/19/2010 | W 71-62 | Old Dominion | 25-8 | Bracket Buster | |
| 2/23/2010 | L 54-55 | @ | Evansville | 7-21 | |
| 2/27/2010 | W 61-55 | Illinois St | 22-7 | ||
| 3/6/2010 | W 55-52 | Southern Illinois | 14-13 | ||
| 3/7/2010 | W 67-52 | vs | Wichita St | 22-7 | Missouri Valley |
| 27-4 | 296-293 |