| Date | Res | Opp | OW-OL | ||
| 11/13/2009 | W 88-72 | UA Pine Bluff | 18-14 | ||
| 11/16/2009 | W 82-58 | Coppin St | 5-22 | ||
| 11/18/2009 | W 88-77 | Texas Southern | 14-16 | ||
| 11/23/2009 | L 72-76 | vs | Gonzaga | 25-6 | Maui Invitational |
| 11/24/2009 | L 87-91 OT | vs | Arizona | 14-16 | Maui Invitational |
| 12/1/2009 | W 78-54 | San Francisco | 10-17 | ||
| 12/4/2009 | L 69-74 | @ | Oregon St | 14-16 | |
| 12/10/2009 | L 62-77 | @ | Colorado St | 14-15 | |
| 12/22/2009 | W 92-58 | CS Northridge | 11-20 | ||
| 12/29/2009 | W 70-59 | Yale | 11-18 | ||
| 1/2/2010 | L 59-84 | @ | Tulsa | 21-11 | |
| 1/5/2010 | W 67-65 | Miami-Ohio | 15-17 | ||
| 1/9/2010 | L 86-103 | @ | Texas | 23-9 | |
| 1/12/2010 | W 78-71 | Baylor | 23-7 | ||
| 1/16/2010 | L 81-87 | Kansas St | 23-7 | ||
| 1/20/2010 | L 78-90 | @ | Oklahoma St | 20-11 | |
| 1/23/2010 | L 63-67 | @ | Texas A&M | 21-9 | |
| 1/27/2010 | W 72-60 | Nebraska | 15-16 | ||
| 1/30/2010 | L 63-64 | @ | Iowa State | 14-16 | |
| 2/3/2010 | L 66-72 OT | Kansas | 30-2 | ||
| 2/6/2010 | L 66-84 | Missouri | 20-9 | ||
| 2/13/2010 | L 51-68 | @ | Kansas St | 23-7 | |
| 2/17/2010 | W 77-67 | Oklahoma | 14-16 | ||
| 2/20/2010 | L 74-94 | @ | Kansas | 30-2 | |
| 2/24/2010 | L 63-92 | @ | Missouri | 20-9 | |
| 2/27/2010 | W 75-72 | Iowa State | 14-16 | ||
| 3/2/2010 | W 81-68 | @ | Nebraska | 15-16 | |
| 3/6/2010 | L 66-84 | Missouri | 20-9 | ||
| 3/10/2010 | L 67-82 | vs | Texas Tech | 17-14 | Big 12 |
| 12-17 | 392-304 |