| Date | Res | Opp | OW-OL | ||
| 11/14/2009 | W 74-67 | Marist | 1-28 | ||
| 11/20/2009 | W 58-56 | Drexel | 17-14 | Legends Classic | |
| 11/22/2009 | L 71-77 | Vermont | 24-9 | ||
| 11/27/2009 | W 83-75 | vs | Massachusetts | 10-20 | Legends Classic |
| 11/28/2009 | L 58-73 | vs | Florida | 21-12 | Legends Classic |
| 12/3/2009 | W 58-44 | Princeton | 19-7 | ||
| 12/6/2009 | W 76-67 | Colgate | 10-18 | ||
| 12/9/2009 | W 66-52 | Monmouth | 12-19 | ||
| 12/15/2009 | W 80-70 OT | Rider | 16-16 | ||
| 12/19/2009 | W 71-62 | NJIT | 7-20 | ||
| 12/22/2009 | W 66-42 | St. Peter's | 16-13 | ||
| 12/28/2009 | L 67-81 | @ | North Carolina | 15-15 | |
| 1/2/2010 | L 58-65 | Cincinnati | 16-14 | ||
| 1/6/2010 | L 52-86 | @ | West Virginia | 26-6 | |
| 1/9/2010 | L 81-94 | @ | Providence | 11-19 | |
| 1/13/2010 | L 65-81 | Syracuse | 27-3 | ||
| 1/16/2010 | L 64-73 | @ | South Florida | 18-12 | |
| 1/20/2010 | L 68-94 | Villanova | 23-7 | ||
| 1/23/2010 | L 63-88 | @ | Georgetown | 22-9 | |
| 1/26/2010 | L 59-82 | @ | Marquette | 22-10 | |
| 1/30/2010 | W 74-73 | Notre Dame | 22-10 | ||
| 2/2/2010 | W 84-72 | St. John's | 16-15 | ||
| 2/6/2010 | L 60-76 | @ | Louisville | 18-12 | |
| 2/14/2010 | W 71-68 | Georgetown | 22-9 | ||
| 2/16/2010 | W 68-64 | @ | DePaul | 8-21 | |
| 2/20/2010 | L 58-76 | Connecticut | 17-14 | ||
| 2/23/2010 | L 70-76 | @ | Seton Hall | 16-13 | |
| 2/27/2010 | W 71-62 | DePaul | 8-21 | ||
| 3/4/2010 | L 74-85 | Seton Hall | 16-13 | ||
| 3/6/2010 | L 60-76 | @ | Louisville | 18-12 | |
| 3/9/2010 | L 68-69 | vs | Cincinnati | 16-14 | Big East |
| 14-17 | 430-356 |