| Date | Res | Opp | OW-OL | ||
| 11/13/2009 | W 96-53 | Bryant | 1-29 | World Vision Invitational | |
| 11/14/2009 | W 76-65 | Bucknell | 14-17 | World Vision Invitational | |
| 11/15/2009 | W 79-77 | Mercer | 13-15 | World Vision Invitational | |
| 11/20/2009 | L 75-84 | @ | Alabama | 15-16 | |
| 11/24/2009 | W 106-64 | Vermont | 25-8 | ||
| 11/28/2009 | L 77-82 | Boston College | 14-17 | ||
| 12/1/2009 | W 76-72 | @ | Northeastern | 20-11 | |
| 12/5/2009 | L 82-86 | @ | Rhode Island | 23-8 | |
| 12/7/2009 | W 78-62 | Brown | 9-19 | ||
| 12/9/2009 | W 110-97 | @ | George Washington | 16-13 | |
| 12/12/2009 | L 73-82 | Iona | 20-10 | ||
| 12/21/2009 | W 87-78 | Yale | 11-18 | ||
| 12/30/2009 | L 78-93 | @ | Notre Dame | 21-11 | |
| 1/3/2010 | W 74-59 | @ | St. John's | 16-15 | |
| 1/6/2010 | L 70-92 | Louisville | 19-12 | ||
| 1/9/2010 | W 94-81 | Rutgers | 14-16 | ||
| 1/14/2010 | W 79-62 | @ | DePaul | 8-22 | |
| 1/17/2010 | L 63-93 | at | Marquette | 20-10 | |
| 1/23/2010 | L 105-109 OT | South Florida | 17-12 | ||
| 1/27/2010 | W 81-66 | Connecticut | 18-13 | ||
| 1/30/2010 | L 88-92 | @ | Cincinnati | 17-14 | |
| 2/2/2010 | L 68-85 | @ | Syracuse | 26-3 | |
| 2/6/2010 | L 79-82 | Marquette | 20-10 | ||
| 2/9/2010 | L 70-79 | Georgetown | 22-10 | ||
| 2/13/2010 | L 81-92 | @ | Villanova | 23-7 | |
| 2/17/2010 | L 74-88 | West Virginia | 26-6 | ||
| 2/23/2010 | L 85-99 | Syracuse | 26-3 | ||
| 2/27/2010 | L 93-99 | @ | South Florida | 17-12 | |
| 3/4/2010 | L 71-73 | @ | Pittsburgh | 23-8 | |
| 3/6/2010 | L 79-82 | Marquette | 20-10 | ||
| 3/9/2010 | L 106-109 | vs | Seton Hall | 17-13 | Big East |
| 12-19 | 468-353 |