| Date | Res | Opp | OW-OL | ||
| 11/13/2009 | W 96-69 | SIU-Edwardsville | 3-23 | ||
| 11/17/2009 | W 80-61 | Northern Illinois | 10-20 | ||
| 11/21/2009 | W 94-48 | Presbyterian | 4-26 | ||
| 11/24/2009 | W 78-64 | Wofford | 25-7 | Las Vegas Invitational | |
| 11/27/2009 | L 58-60 | vs | Utah | 13-16 | Las Vegas Invitational |
| 11/28/2009 | L 68-72 | vs | Bradley | 15-14 | Las Vegas Invitational |
| 12/2/2009 | W 76-74 | @ | Clemson | 21-10 | Big Ten-ACC Challenge |
| 12/5/2009 | W 84-77 | Boise St | 13-17 | ||
| 12/8/2009 | W 79-68 | Vanderbilt | 23-7 | ||
| 12/13/2009 | W 88-53 | Western Michigan | 18-14 | ||
| 12/19/2009 | L 67-70 | vs | Georgia | 14-16 | |
| 12/23/2009 | L 68-81 | vs | Missouri | 22-9 | |
| 12/30/2009 | W 89-83 OT | Northwestern | 19-11 | ||
| 1/2/2010 | L 83-85 OT | vs | Gonzaga | 25-6 | |
| 1/5/2010 | W 59-42 | Iowa | 10-20 | ||
| 1/9/2010 | W 66-60 | @ | Indiana | 9-19 | |
| 1/12/2010 | W 54-53 | Penn State | 11-18 | ||
| 1/16/2010 | L 63-73 | @ | Michigan St | 23-7 | |
| 1/19/2010 | L 78-84 | Purdue | 24-5 | ||
| 1/23/2010 | L 68-73 | @ | Northwestern | 19-11 | |
| 1/27/2010 | W 77-67 | @ | Penn State | 11-18 | |
| 1/30/2010 | W 72-70 | Indiana | 9-19 | ||
| 2/3/2010 | W 57-49 | @ | Iowa | 10-20 | |
| 2/6/2010 | W 78-73 | Michigan St | 23-7 | ||
| 2/9/2010 | W 63-56 | @ | Wisconsin | 23-6 | |
| 2/14/2010 | L 53-72 | Ohio State | 24-7 | ||
| 2/20/2010 | L 65-75 | @ | Purdue | 24-5 | |
| 2/23/2010 | W 51-44 | @ | Michigan | 14-17 | |
| 2/27/2010 | L 60-62 | Minnesota | 21-13 | ||
| 3/2/2010 | L 57-73 | @ | Ohio State | 24-7 | |
| 3/6/2010 | W 78-73 | Michigan St | 23-7 | ||
| 3/7/2010 | L 57-72 | Wisconsin | 23-6 | ||
| 3/12/2010 | W 58-54 | vs | Wisconsin | 23-6 | Big Ten |
| 3/13/2010 | L 81-88 2 OT | vs | Ohio State | 24-7 | Big Ten |
| 20-14 | 384-308 |