| Date | Res | Opp | OW-OL | ||
| 11/11/2009 | L 60-100 | at | Syracuse | 27-3 | Coaches vs Cancer |
| 11/16/2009 | L 61-80 | @ | Penn State | 10-20 | |
| 11/20/2009 | L 59-71 | vs | Detroit | 17-14 | Coaches vs Cancer |
| 11/21/2009 | W 107-76 | vs | Alcorn St | 1-29 | Coaches vs Cancer |
| 11/22/2009 | L 66-71 | @ | Albany | 6-25 | Coaches vs Cancer |
| 12/3/2009 | W 63-57 | Mt St. Mary's | 16-13 | ||
| 12/5/2009 | W 73-70 | Wagner | 5-25 | ||
| 12/12/2009 | L 54-59 | @ | Duquesne | 14-15 | |
| 12/15/2009 | W 78-70 | @ | Cleveland St | 15-15 | |
| 12/19/2009 | L 52-65 | Appalachian St | 19-11 | ||
| 12/22/2009 | L 57-71 | Kent St | 21-9 | ||
| 12/30/2009 | W 72-67 | @ | Youngstown St | 6-22 | |
| 1/2/2010 | W 81-79 | Ohio | 20-14 | ||
| 1/4/2010 | W 78-75 | Morgan St | 27-8 | ||
| 1/7/2010 | L 64-74 | @ | Long Island | 13-17 | |
| 1/9/2010 | W 67-63 | @ | St. Francis (NY) | 12-16 | |
| 1/14/2010 | W 80-73 | Fairleigh Dickinson | 12-19 | ||
| 1/16/2010 | W 78-67 | Monmouth | 12-18 | ||
| 1/21/2010 | W 65-50 | @ | Fairleigh Dickinson | 12-19 | |
| 1/23/2010 | W 66-53 | @ | Monmouth | 12-18 | |
| 1/28/2010 | W 66-58 | Long Island | 13-17 | ||
| 1/30/2010 | W 74-56 | St. Francis (NY) | 12-16 | ||
| 2/4/2010 | W 76-67 | @ | St. Francis (PA) | 11-17 | |
| 2/6/2010 | W 75-64 | St. Francis (PA) | 11-17 | ||
| 2/8/2010 | L 53-77 | @ | Pittsburgh | 23-8 | |
| 2/11/2010 | W 60-34 | @ | Bryant | 1-28 | |
| 2/13/2010 | W 52-42 | @ | Bryant | 1-28 | |
| 2/18/2010 | W 64-39 | Sacred Heart | 14-15 | ||
| 2/20/2010 | L 79-87 | Quinnipiac | 23-8 | ||
| 2/25/2010 | W 76-55 | @ | Wagner | 5-25 | |
| 2/27/2010 | L 61-63 | @ | Mt St. Mary's | 16-13 | |
| 3/4/2010 | W 71-63 | Central Connecticut | 13-17 | Northeast | |
| 3/6/2010 | W 75-64 | St. Francis (PA) | 11-17 | ||
| 3/7/2010 | W 80-62 | Mt St. Mary's | 16-13 | Northeast | |
| 3/10/2010 | W 52-50 | @ | Quinnipiac | 23-8 | Northeast |
| 24-11 | 338-386 |