| Date | Res | Opp | OW-OL | ||
| 11/11/2009 | L 61-95 | at | California | 22-10 | Coaches vs Cancer |
| 11/15/2009 | W 86-80 | Western Michigan | 18-14 | ||
| 11/20/2009 | W 71-59 | vs | Robert Morris | 24-10 | Coaches vs Cancer |
| 11/21/2009 | W 66-54 | @ | Albany | 7-24 | Coaches vs Cancer |
| 11/22/2009 | W 79-59 | vs | Alcorn St | 1-29 | Coaches vs Cancer |
| 11/28/2009 | L 66-68 OT | @ | DePaul | 7-23 | |
| 12/3/2009 | W 82-71 | Youngstown St | 6-21 | ||
| 12/5/2009 | W 69-62 | Cleveland St | 15-14 | ||
| 12/8/2009 | L 69-70 | Tennessee St | 9-23 | ||
| 12/13/2009 | L 64-75 | @ | Michigan | 13-18 | |
| 12/19/2009 | W 73-69 | Bowling Green | 13-16 | ||
| 12/22/2009 | W 76-58 | Central Michigan | 14-15 | ||
| 12/31/2009 | L 56-60 | @ | UIC | 7-21 | |
| 1/2/2010 | W 59-42 | @ | Loyola (Chicago) | 12-15 | |
| 1/8/2010 | W 77-67 | Valparaiso | 11-15 | ||
| 1/10/2010 | L 62-64 | Butler | 26-4 | ||
| 1/14/2010 | W 81-65 | @ | UW Milwaukee | 16-13 | |
| 1/16/2010 | L 72-74 | @ | UW Green Bay | 18-11 | |
| 1/23/2010 | L 59-61 | Wright St | 17-13 | ||
| 1/28/2010 | W 83-63 | Loyola (Chicago) | 12-15 | ||
| 1/30/2010 | W 76-73 | UIC | 7-21 | ||
| 2/4/2010 | L 58-63 | @ | Butler | 26-4 | |
| 2/6/2010 | L 70-74 | @ | Valparaiso | 11-15 | |
| 2/8/2010 | W 92-72 | Chicago St | 6-21 | ||
| 2/11/2010 | L 62-64 | UW Green Bay | 18-11 | ||
| 2/13/2010 | L 60-71 | UW Milwaukee | 16-13 | ||
| 2/17/2010 | L 53-70 | @ | Wright St | 17-13 | |
| 2/20/2010 | W 68-66 | Eastern Michigan | 16-14 | Bracket Buster | |
| 2/25/2010 | W 65-54 | @ | Cleveland St | 15-14 | |
| 2/27/2010 | W 62-54 | @ | Youngstown St | 6-21 | |
| 3/2/2010 | W 89-82 | @ | Valparaiso | 11-15 | Horizon |
| 3/6/2010 | L 70-74 | @ | Valparaiso | 11-15 | |
| 18-14 | 278-344 |