| Date | Res | Opp | OW-OL | ||
| 11/9/2009 | L 60-100 | at | Ohio State | 26-7 | Coaches vs Cancer |
| 11/13/2009 | L 68-130 | @ | Arkansas | 14-17 | |
| 11/15/2009 | L 66-82 | @ | UL Monroe | 8-19 | |
| 11/20/2009 | L 55-71 | @ | Albany | 6-25 | Coaches vs Cancer |
| 11/21/2009 | L 76-107 | vs | Robert Morris | 23-11 | Coaches vs Cancer |
| 11/22/2009 | L 59-79 | vs | Detroit | 17-14 | Coaches vs Cancer |
| 11/25/2009 | L 67-83 | @ | South Alabama | 13-16 | South Alabama Tournament |
| 11/26/2009 | L 53-68 | vs | Utah Valley | 8-17 | South Alabama Tournament |
| 11/30/2009 | L 52-87 | @ | Wichita St | 22-9 | |
| 12/2/2009 | L 31-98 | @ | Kansas | 31-2 | |
| 12/19/2009 | L 41-101 | @ | UTEP | 25-6 | |
| 12/21/2009 | L 72-97 | @ | New Mexico St | 21-10 | |
| 12/30/2009 | L 64-68 | Central Michigan | 13-16 | ||
| 1/4/2010 | L 56-89 | @ | Texas Southern | 12-17 | |
| 1/6/2010 | L 60-82 | @ | Prairie View A&M | 12-13 | |
| 1/11/2010 | L 74-82 OT | Grambling St | 5-20 | ||
| 1/16/2010 | L 70-80 | @ | Miss Valley St | 8-22 | |
| 1/18/2010 | L 59-93 | @ | UA Pine Bluff | 16-15 | |
| 1/23/2010 | L 62-69 | Alabama St | 11-15 | ||
| 1/25/2010 | L 70-84 | Alabama A&M | 5-16 | ||
| 1/27/2010 | L 51-63 | Jackson St | 15-12 | ||
| 1/30/2010 | L 75-84 | @ | Southern U | 3-24 | |
| 2/6/2010 | L 64-85 | @ | Jackson St | 15-12 | |
| 2/8/2010 | L 58-73 | @ | Grambling St | 5-20 | |
| 2/13/2010 | W 55-54 | Miss Valley St | 8-22 | ||
| 2/15/2010 | L 45-59 | UA Pine Bluff | 16-15 | ||
| 2/20/2010 | L 64-91 | @ | Alabama St | 11-15 | |
| 2/22/2010 | L 60-72 | @ | Alabama A&M | 5-16 | |
| 2/27/2010 | L 57-60 | Southern U | 3-24 | ||
| 3/4/2010 | L 67-84 | Texas Southern | 12-17 | ||
| 3/6/2010 | L 64-85 | @ | Jackson St | 15-12 | |
| 1-30 | 314-323 |