| Date | Res | Opp | OW-OL | ||
| 11/14/2009 | W 71-67 | @ | Alabama | 16-15 | |
| 11/18/2009 | W 74-61 | @ | Massachusetts | 10-20 | Legends Classic |
| 11/20/2009 | L 79-89 | Seton Hall | 17-13 | ||
| 11/24/2009 | L 73-88 | @ | Syracuse | 27-3 | |
| 11/27/2009 | W 78-60 | vs | Toledo | 3-28 | Legends Classic |
| 11/28/2009 | W 67-59 | vs | Vermont | 25-8 | Legends Classic |
| 11/29/2009 | W 61-54 | @ | Drexel | 17-14 | Legends Classic |
| 12/2/2009 | W 104-98 OT | @ | Bucknell | 14-17 | |
| 12/6/2009 | W 78-66 | Saint Joseph's | 10-19 | ||
| 12/20/2009 | W 91-88 OT | vs | Davidson | 15-13 | MSG Holiday Festival |
| 12/21/2009 | W 71-66 | @ | St. John's | 16-15 | MSG Holiday Festival |
| 12/29/2009 | W 78-75 | @ | La Salle | 12-17 | |
| 1/2/2010 | W 75-49 | Bryant | 1-29 | ||
| 1/6/2010 | L 66-71 | @ | Kansas | 31-2 | |
| 1/8/2010 | W 71-65 | @ | South Dakota | 18-8 | |
| 1/16/2010 | W 74-53 | Columbia | 11-15 | ||
| 1/23/2010 | W 77-51 | @ | Columbia | 11-15 | |
| 1/29/2010 | W 71-37 | Dartmouth | 4-21 | ||
| 1/30/2010 | W 86-50 | Harvard | 20-5 | ||
| 2/5/2010 | W 90-71 | Yale | 11-17 | ||
| 2/6/2010 | W 74-60 | Brown | 9-18 | ||
| 2/12/2010 | L 64-79 | @ | Pennsylvania | 5-21 | |
| 2/13/2010 | W 48-45 | @ | Princeton | 19-6 | |
| 2/19/2010 | W 79-70 | @ | Harvard | 20-5 | |
| 2/20/2010 | W 88-70 | @ | Dartmouth | 4-21 | |
| 2/26/2010 | W 50-47 | Princeton | 19-6 | ||
| 2/27/2010 | W 68-48 | Pennsylvania | 5-21 | ||
| 3/5/2010 | W 90-71 | Yale | 11-17 | ||
| 3/6/2010 | W 74-60 | Brown | 9-18 | ||
| 25-4 | 311-324 |