| Date | Res | Opp | OW-OL | ||
| 11/13/2009 | W 87-77 | @ | Holy Cross | 10-21 | |
| 11/15/2009 | W 87-85 3 OT | William & Mary | 21-9 | ||
| 11/20/2009 | W 77-51 | Bryant | 1-29 | ||
| 11/23/2009 | L 53-56 | @ | Army | 12-15 | |
| 11/25/2009 | W 78-60 | New Hampshire | 11-17 | ||
| 11/29/2009 | W 78-70 | @ | Boston U | 19-12 | |
| 12/2/2009 | W 85-64 | Rice | 7-22 | ||
| 12/6/2009 | L 73-79 | @ | Connecticut | 17-14 | |
| 12/9/2009 | W 74-67 | @ | Boston College | 15-16 | |
| 12/23/2009 | L 70-86 | @ | Georgetown | 22-10 | |
| 12/30/2009 | W 66-53 | George Washington | 16-13 | ||
| 1/2/2010 | W 92-71 | @ | Seattle | 16-13 | |
| 1/4/2010 | W 74-66 | @ | Santa Clara | 10-19 | |
| 1/9/2010 | W 76-47 | Dartmouth | 4-21 | ||
| 1/23/2010 | W 62-58 | @ | Dartmouth | 4-21 | |
| 1/29/2010 | W 74-45 | @ | Columbia | 11-15 | |
| 1/30/2010 | L 50-86 | @ | Cornell | 23-4 | |
| 2/5/2010 | L 53-56 | Princeton | 17-8 | ||
| 2/6/2010 | W 80-66 | Pennsylvania | 6-20 | ||
| 2/12/2010 | W 82-79 | @ | Yale | 11-17 | |
| 2/13/2010 | W 81-67 | @ | Brown | 9-18 | |
| 2/19/2010 | L 70-79 | Cornell | 23-4 | ||
| 2/20/2010 | W 77-57 | Columbia | 11-15 | ||
| 2/26/2010 | W 91-71 | Brown | 9-18 | ||
| 2/27/2010 | W 78-58 | Yale | 11-17 | ||
| 3/5/2010 | L 53-56 | Princeton | 17-8 | ||
| 3/6/2010 | W 80-66 | Pennsylvania | 6-20 | ||
| 20-7 | 258-313 |