| Date | Res | Opp | OW-OL | ||
| 11/13/2009 | W 77-67 OT | Drexel | 17-14 | ||
| 11/17/2009 | W 69-67 | Holy Cross | 10-21 | ||
| 11/20/2009 | W 84-80 | vs | Boston College | 15-16 | Paradise Jam |
| 11/22/2009 | L 60-85 | vs | Purdue | 25-5 | Paradise Jam |
| 11/23/2009 | L 51-58 | vs | DePaul | 7-23 | Paradise Jam |
| 11/30/2009 | L 73-81 | @ | Rider | 15-17 | |
| 12/6/2009 | L 66-78 | @ | Cornell | 24-4 | |
| 12/9/2009 | L 89-97 | Villanova | 23-7 | ||
| 12/12/2009 | L 74-97 | @ | Minnesota | 21-13 | |
| 12/20/2009 | W 77-66 | Lehigh | 23-9 | ||
| 12/29/2009 | L 75-92 | @ | Siena | 26-6 | |
| 1/2/2010 | L 62-70 | Princeton | 18-8 | ||
| 1/6/2010 | L 46-73 | @ | Temple | 26-5 | |
| 1/9/2010 | W 82-69 | Fordham | 2-25 | ||
| 1/13/2010 | L 74-101 | @ | Rhode Island | 22-8 | |
| 1/16/2010 | L 65-68 | @ | St. Bonaventure | 13-14 | |
| 1/18/2010 | W 64-57 | Towson | 9-19 | ||
| 1/23/2010 | W 60-59 | Dayton | 21-10 | ||
| 1/25/2010 | W 85-64 | @ | Pennsylvania | 6-21 | |
| 1/27/2010 | L 80-87 | Massachusetts | 8-21 | ||
| 1/31/2010 | L 71-74 | @ | Duquesne | 14-15 | |
| 2/3/2010 | L 58-68 | Richmond | 25-8 | ||
| 2/7/2010 | W 78-71 | St. Bonaventure | 13-14 | ||
| 2/9/2010 | L 52-56 | Saint Louis | 18-11 | ||
| 2/14/2010 | L 62-70 | @ | Massachusetts | 8-21 | |
| 2/17/2010 | L 52-88 | @ | Xavier | 22-9 | |
| 2/20/2010 | L 67-75 OT | Temple | 26-5 | ||
| 2/24/2010 | L 58-95 | @ | Charlotte | 19-12 | |
| 3/3/2010 | W 80-71 | @ | George Washington | 16-13 | |
| 3/9/2010 | L 76-87 | @ | Rhode Island | 22-8 | Atlantic 10 |
| 10-20 | 445-334 |