| Date | Res | Opp | OW-OL | ||
| 11/14/2009 | L 62-73 | @ | Butler | 27-4 | |
| 11/19/2009 | L 58-65 | vs | South Florida | 18-12 | C of Charleston Classic |
| 11/20/2009 | L 70-84 | vs | La Salle | 11-18 | C of Charleston Classic |
| 11/22/2009 | L 57-59 | vs | Penn State | 10-20 | C of Charleston Classic |
| 11/28/2009 | L 65-75 | Rhode Island | 23-8 | ||
| 12/3/2009 | W 74-63 | @ | The Citadel | 14-13 | |
| 12/5/2009 | L 55-67 | @ | Coll of Charleston | 20-10 | |
| 12/12/2009 | L 91-103 | vs | Gonzaga | 25-6 | |
| 12/20/2009 | L 88-91 OT | vs | Cornell | 24-4 | MSG Holiday Festival |
| 12/21/2009 | W 61-52 | vs | Hofstra | 17-13 | MSG Holiday Festival |
| 12/28/2009 | W 79-50 | Pennsylvania | 6-21 | ||
| 12/30/2009 | W 63-61 | Massachusetts | 10-20 | ||
| 1/4/2010 | W 66-56 | Samford | 8-19 | ||
| 1/9/2010 | L 68-78 | Appalachian St | 18-11 | ||
| 1/13/2010 | W 86-81 | @ | Furman | 11-15 | |
| 1/16/2010 | L 62-68 | @ | Wofford | 23-8 | |
| 1/20/2010 | L 67-77 | Western Carolina | 17-11 | ||
| 1/23/2010 | W 91-87 | @ | Georgia So | 7-20 | |
| 1/28/2010 | W 86-71 | Coll of Charleston | 20-10 | ||
| 1/30/2010 | W 67-63 OT | The Citadel | 14-13 | ||
| 2/6/2010 | W 84-74 | Georgia So | 7-20 | ||
| 2/11/2010 | L 56-66 | @ | Appalachian St | 18-11 | |
| 2/13/2010 | W 75-72 | @ | Western Carolina | 17-11 | |
| 2/17/2010 | L 51-73 | Wofford | 23-8 | ||
| 2/20/2010 | W 61-58 | Furman | 11-15 | ||
| 2/22/2010 | L 73-78 | @ | Chattanooga | 11-18 | |
| 2/24/2010 | W 60-56 | UNC Greensboro | 7-22 | ||
| 2/27/2010 | W 99-96 2 OT | @ | Elon | 8-21 | |
| 3/6/2010 | W 84-74 | Georgia So | 7-20 | ||
| 15-14 | 315-294 |