| Date | Res | Opp | OW-OL | ||
| 11/13/2009 | L 50-87 | @ | Minnesota | 21-13 | |
| 11/16/2009 | W 71-67 | @ | Central Arkansas | 5-20 | Hall of Fame Classic |
| 11/19/2009 | W 92-89 | @ | Lipscomb | 16-13 | |
| 11/20/2009 | L 59-92 | @ | Memphis | 21-10 | Hall of Fame Classic |
| 11/23/2009 | L 56-77 | Oakland | 23-8 | Hall of Fame Classic | |
| 11/25/2009 | W 72-65 | @ | Southern Utah | 5-22 | |
| 11/27/2009 | L 75-112 | @ | Kansas | 31-2 | Hall of Fame Classic |
| 12/1/2009 | L 90-91 2 OT | Evansville | 7-22 | ||
| 12/5/2009 | L 72-83 | @ | Jacksonville St | 8-19 | |
| 12/12/2009 | W 86-81 OT | Ball State | 14-15 | ||
| 1/2/2010 | W 82-73 | @ | SE Missouri St | 6-22 | |
| 1/4/2010 | L 93-97 OT | @ | Eastern Illinois | 17-10 | |
| 1/7/2010 | L 64-77 | Morehead St | 18-9 | ||
| 1/9/2010 | L 73-78 | Eastern Kentucky | 17-12 | ||
| 1/14/2010 | W 76-63 | @ | UT Martin | 2-24 | |
| 1/16/2010 | L 66-88 | @ | Murray St | 25-4 | |
| 1/21/2010 | W 94-90 | Austin Peay | 14-14 | ||
| 1/23/2010 | W 61-56 | Tennessee St | 9-22 | ||
| 1/28/2010 | W 75-65 | Eastern Illinois | 17-10 | ||
| 1/30/2010 | W 82-68 | SE Missouri St | 6-22 | ||
| 2/4/2010 | L 58-76 | @ | Eastern Kentucky | 17-12 | |
| 2/6/2010 | L 75-84 | @ | Morehead St | 18-9 | |
| 2/11/2010 | L 62-94 | Murray St | 25-4 | ||
| 2/13/2010 | W 70-61 | UT Martin | 2-24 | ||
| 2/15/2010 | L 102-109 2 OT | @ | Tennessee St | 9-22 | |
| 2/18/2010 | L 72-77 OT | @ | Austin Peay | 14-14 | |
| 2/20/2010 | L 68-81 | @ | Appalachian St | 19-11 | Bracket Buster |
| 2/27/2010 | W 72-62 | Jacksonville St | 8-19 | ||
| 3/2/2010 | W 68-65 | @ | Austin Peay | 14-14 | Ohio Valley |
| 3/6/2010 | L 75-84 | @ | Morehead St | 18-9 | |
| 13-17 | 278-272 |