| Date | Res | Opp | OW-OL | ||
| 11/14/2009 | L 63-91 | @ | Southern Illinois | 13-16 | |
| 11/17/2009 | L 68-83 | @ | Missouri | 22-9 | |
| 11/25/2009 | L 66-80 | @ | Arkansas St | 14-14 | |
| 12/3/2009 | L 66-74 | Morehead St | 19-9 | ||
| 12/5/2009 | L 74-85 | Eastern Kentucky | 17-12 | ||
| 12/9/2009 | L 51-79 | @ | Missouri St | 20-11 | |
| 12/12/2009 | L 71-81 | Central Arkansas | 4-21 | ||
| 12/19/2009 | L 63-84 | @ | Evansville | 7-22 | |
| 12/22/2009 | L 68-95 | @ | Florida St | 21-9 | |
| 1/4/2010 | L 59-83 | @ | Murray St | 25-4 | |
| 1/7/2010 | L 72-90 | @ | Austin Peay | 13-16 | |
| 1/9/2010 | L 59-73 | @ | Tennessee St | 7-23 | |
| 1/14/2010 | L 63-76 | Tennessee Tech | 11-17 | ||
| 1/16/2010 | L 63-73 | Jacksonville St | 7-20 | ||
| 1/21/2010 | L 63-77 | @ | SE Missouri St | 5-23 | |
| 1/23/2010 | L 46-60 | @ | Eastern Illinois | 16-11 | |
| 1/25/2010 | W 68-53 | SIU-Edwardsville | 3-23 | ||
| 1/30/2010 | L 45-77 | Murray St | 25-4 | ||
| 2/4/2010 | L 69-74 | Austin Peay | 13-16 | ||
| 2/6/2010 | L 68-74 | Tennessee St | 7-23 | ||
| 2/9/2010 | W 73-70 | SE Missouri St | 5-23 | ||
| 2/11/2010 | L 68-80 | @ | Jacksonville St | 7-20 | |
| 2/13/2010 | L 61-70 | @ | Tennessee Tech | 11-17 | |
| 2/16/2010 | L 68-83 | Eastern Illinois | 16-11 | ||
| 2/20/2010 | L 52-68 | @ | Ball State | 13-16 | Bracket Buster |
| 2/25/2010 | L 60-84 | @ | Eastern Kentucky | 17-12 | |
| 2/27/2010 | L 63-73 | @ | Morehead St | 19-9 | |
| 3/6/2010 | L 68-74 | Tennessee St | 7-23 | ||
| 2-26 | 237-276 |