| Date | Res | Opp | OW-OL | ||
| 11/14/2009 | W 73-62 | Davidson | 15-13 | ||
| 11/18/2009 | W 67-54 | @ | Northwestern | 20-11 | |
| 11/21/2009 | W 64-60 | @ | Evansville | 8-21 | |
| 11/26/2009 | L 73-82 | vs | Minnesota | 21-13 | 76 Classic |
| 11/27/2009 | W 69-67 | vs | UCLA | 14-17 | 76 Classic |
| 11/29/2009 | L 69-70 | vs | Clemson | 20-11 | 76 Classic |
| 12/2/2009 | W 59-38 | @ | Ball State | 14-15 | |
| 12/5/2009 | W 84-67 | Valparaiso | 13-15 | ||
| 12/8/2009 | L 65-72 | vs | Georgetown | 22-10 | Jimmy V Classic |
| 12/12/2009 | W 74-66 | Ohio State | 27-6 | ||
| 12/19/2009 | W 69-68 | Xavier | 23-8 | ||
| 12/22/2009 | L 57-67 | @ | UAB | 23-7 | |
| 12/31/2009 | W 72-49 | UW Green Bay | 20-9 | ||
| 1/2/2010 | W 80-67 | UW Milwaukee | 17-12 | ||
| 1/8/2010 | W 77-65 | @ | Wright St | 19-9 | |
| 1/10/2010 | W 64-62 | @ | Detroit | 18-12 | |
| 1/14/2010 | W 64-55 | Cleveland St | 15-14 | ||
| 1/16/2010 | W 91-61 | Youngstown St | 6-21 | ||
| 1/21/2010 | W 48-47 | @ | Loyola (Chicago) | 12-15 | |
| 1/23/2010 | W 84-55 | @ | UIC | 8-20 | |
| 1/29/2010 | W 75-57 | @ | UW Green Bay | 20-9 | |
| 1/31/2010 | W 73-66 | @ | UW Milwaukee | 17-12 | |
| 2/4/2010 | W 63-58 | Detroit | 18-12 | ||
| 2/6/2010 | W 74-62 | Wright St | 19-9 | ||
| 2/8/2010 | W 62-47 | Loyola (Chicago) | 12-15 | ||
| 2/11/2010 | W 68-57 | @ | Youngstown St | 6-21 | |
| 2/13/2010 | W 70-59 | @ | Cleveland St | 15-14 | |
| 2/17/2010 | W 73-55 | UIC | 8-20 | ||
| 2/20/2010 | W 70-53 | Siena | 27-5 | Bracket Buster | |
| 2/26/2010 | W 74-69 | @ | Valparaiso | 13-15 | |
| 3/6/2010 | W 74-62 | Wright St | 19-9 | ||
| 3/9/2010 | W 70-45 | Wright St | 19-9 | Horizon | |
| 28-4 | 362-264 |