| Date | Res | Opp | OW-OL | ||
| 11/9/2009 | L 72-88 | at | North Carolina | 15-15 | Coaches vs Cancer |
| 11/13/2009 | L 70-99 | @ | Monmouth | 11-20 | |
| 11/15/2009 | L 49-81 | @ | Tulsa | 21-11 | |
| 11/20/2009 | W 83-74 | NCCU | 4-21 | Coaches vs Cancer | |
| 11/22/2009 | L 68-81 | James Madison | 11-19 | Coaches vs Cancer | |
| 11/23/2009 | L 71-84 | Murray St | 26-4 | Coaches vs Cancer | |
| 11/28/2009 | L 67-81 | @ | Eastern Kentucky | 18-12 | |
| 11/30/2009 | L 62-67 | @ | Bowling Green | 12-17 | |
| 12/3/2009 | W 61-56 | @ | Florida A&M | 8-21 | |
| 12/6/2009 | L 62-82 | @ | Florida St | 21-9 | |
| 12/12/2009 | L 64-81 | @ | Florida Gulf Coast | 7-22 | |
| 12/17/2009 | L 53-59 | @ | Denver | 18-13 | |
| 12/20/2009 | W 80-70 OT | @ | North Texas | 21-7 | |
| 12/22/2009 | L 63-93 | @ | Sam Houston | 21-6 | |
| 12/31/2009 | L 59-71 | South Alabama | 12-16 | ||
| 1/2/2010 | L 58-68 | @ | New Orleans | 5-22 | |
| 1/7/2010 | W 62-56 | UL Monroe | 9-18 | ||
| 1/9/2010 | L 68-84 | Troy | 15-13 | ||
| 1/14/2010 | W 65-58 | @ | Middle Tenn St | 17-12 | |
| 1/16/2010 | L 64-81 | @ | Western Kentucky | 19-13 | |
| 1/21/2010 | L 61-76 | Arkansas St | 14-14 | ||
| 1/23/2010 | W 96-81 | UA Little Rock | 6-21 | ||
| 1/30/2010 | L 88-106 | @ | Florida Atlantic | 10-16 | |
| 2/4/2010 | L 63-83 | @ | UL Lafayette | 12-15 | |
| 2/6/2010 | L 66-68 | North Texas | 21-7 | ||
| 2/11/2010 | L 65-69 OT | @ | South Alabama | 12-16 | |
| 2/13/2010 | L 78-81 | @ | Troy | 15-13 | |
| 2/18/2010 | L 74-77 | Florida Atlantic | 10-16 | ||
| 2/25/2010 | L 71-74 | Middle Tenn St | 17-12 | ||
| 2/27/2010 | L 61-88 | Western Kentucky | 19-13 | ||
| 3/6/2010 | L 66-68 | North Texas | 21-7 | ||
| 6-25 | 333-357 |