| Date | Res | Opp | OW-OL | ||
| 11/18/2009 | W 78-57 | @ | Brown | 9-19 | |
| 11/22/2009 | W 92-75 | Holy Cross | 10-21 | ||
| 11/24/2009 | W 75-58 | Stony Brook | 20-8 | ||
| 11/28/2009 | W 75-65 | @ | Davidson | 15-13 | |
| 12/2/2009 | L 80-82 | @ | VCU | 20-9 | |
| 12/5/2009 | W 86-82 | Providence | 12-18 | ||
| 12/8/2009 | W 83-74 | Quinnipiac | 24-8 | ||
| 12/10/2009 | W 79-76 | Northeastern | 20-11 | ||
| 12/13/2009 | W 80-69 | @ | Boston College | 15-16 | |
| 12/20/2009 | W 89-84 | Fairfield | 22-9 | ||
| 12/29/2009 | W 80-79 | @ | Drexel | 17-14 | |
| 1/2/2010 | W 63-59 | vs | Oklahoma St | 21-10 | |
| 1/5/2010 | W 68-63 | @ | Akron | 24-8 | |
| 1/10/2010 | L 64-68 OT | Temple | 25-5 | ||
| 1/13/2010 | W 101-74 | Saint Joseph's | 10-18 | ||
| 1/16/2010 | W 85-67 | @ | Fordham | 2-24 | |
| 1/20/2010 | W 75-67 | Duquesne | 15-14 | ||
| 1/23/2010 | L 61-72 | @ | Xavier | 22-9 | |
| 1/26/2010 | W 65-64 | @ | Dayton | 21-10 | |
| 1/30/2010 | W 72-66 | George Washington | 16-13 | ||
| 2/2/2010 | W 90-83 | @ | La Salle | 12-17 | |
| 2/6/2010 | W 93-85 | Massachusetts | 10-19 | ||
| 2/10/2010 | L 67-69 | Richmond | 25-8 | ||
| 2/13/2010 | L 56-78 | @ | Temple | 25-5 | |
| 2/17/2010 | L 57-62 | @ | Saint Louis | 18-10 | |
| 2/20/2010 | W 101-75 | Fordham | 2-24 | ||
| 2/27/2010 | L 74-81 | @ | St. Bonaventure | 13-15 | |
| 3/3/2010 | W 80-58 | Charlotte | 20-11 | ||
| 3/6/2010 | W 93-85 | Massachusetts | 10-19 | ||
| 3/9/2010 | W 87-76 | Saint Joseph's | 10-18 | Atlantic 10 | |
| 3/12/2010 | W 63-47 | vs | Saint Louis | 18-10 | Atlantic 10 |
| 3/13/2010 | L 44-57 | vs | Temple | 25-5 | Atlantic 10 |
| 24-8 | 438-337 |