| Date | Res | Opp | OW-OL | ||
| 11/16/2009 | W 77-72 | UT Pan American | 5-27 | ||
| 11/19/2009 | L 66-74 | @ | Middle Tenn St | 17-13 | Global Sports Classic |
| 11/21/2009 | L 54-77 | @ | Texas Tech | 17-14 | |
| 11/23/2009 | L 46-71 | @ | Ohio | 19-15 | Global Sports Classic |
| 11/25/2009 | L 74-87 | @ | Marshall | 19-9 | Global Sports Classic |
| 11/28/2009 | W 74-73 | North Carolina A&T | 9-21 | Global Sports Classic | |
| 12/2/2009 | L 55-62 | @ | Denver | 18-13 | |
| 12/6/2009 | L 78-96 | @ | Hawai'i | 8-20 | |
| 12/19/2009 | L 60-68 | UL Lafayette | 12-15 | ||
| 12/23/2009 | W 77-61 | Rice | 7-22 | ||
| 1/2/2010 | W 70-67 | Tulane | 7-22 | ||
| 1/4/2010 | W 87-68 | Arkansas St | 15-13 | ||
| 1/9/2010 | L 56-78 | @ | SE Louisiana | 13-13 | |
| 1/13/2010 | W 71-68 | UT Arlington | 12-12 | ||
| 1/16/2010 | W 79-78 | McNeese St | 7-19 | ||
| 1/20/2010 | L 64-81 | @ | Texas A&M CC | 12-15 | |
| 1/23/2010 | L 92-97 OT | Texas St | 9-16 | ||
| 1/27/2010 | L 63-90 | @ | Sam Houston | 20-6 | |
| 1/30/2010 | W 64-57 | @ | UT San Antonio | 15-10 | |
| 2/3/2010 | W 73-65 | Central Arkansas | 5-20 | ||
| 2/6/2010 | W 49-46 | Stephen F. Austin | 20-7 | ||
| 2/13/2010 | L 67-81 | @ | Texas St | 9-16 | |
| 2/17/2010 | L 54-66 | Sam Houston | 20-6 | ||
| 2/20/2010 | L 79-82 | @ | Northwestern St | 6-18 | |
| 2/24/2010 | L 71-75 | @ | UT Arlington | 12-12 | |
| 2/27/2010 | L 74-76 | UT San Antonio | 15-10 | ||
| 3/3/2010 | L 55-79 | Texas A&M CC | 12-15 | ||
| 3/6/2010 | W 49-46 | Stephen F. Austin | 20-7 | ||
| 11-17 | 272-340 |