| Date | Res | Opp | OW-OL | ||
| 11/15/2009 | L 63-79 | @ | Marshall | 19-9 | Global Sports Classic |
| 11/17/2009 | L 82-93 | @ | Ohio | 19-15 | Global Sports Classic |
| 11/23/2009 | W 65-56 | Middle Tenn St | 18-12 | Global Sports Classic | |
| 11/25/2009 | L 66-81 | @ | UTEP | 25-6 | |
| 11/26/2009 | L 68-84 | @ | New Mexico St | 21-10 | |
| 11/28/2009 | L 73-74 | @ | Lamar | 10-17 | Global Sports Classic |
| 12/5/2009 | W 93-84 OT | @ | Norfolk St | 11-18 | |
| 12/13/2009 | L 65-90 | @ | Northwestern | 19-12 | |
| 12/21/2009 | L 59-80 | @ | Miami (FL) | 18-13 | |
| 12/23/2009 | L 78-99 | @ | Tennessee | 24-8 | |
| 12/30/2009 | L 54-78 | @ | Tulane | 6-23 | |
| 1/9/2010 | L 66-70 | @ | Florida A&M | 7-22 | |
| 1/11/2010 | L 65-66 | @ | Bethune Cookman | 14-16 | |
| 1/16/2010 | L 77-82 | Howard | 5-25 | ||
| 1/18/2010 | L 55-65 | Hampton | 13-18 | ||
| 1/23/2010 | W 67-58 | @ | South Carolina St | 16-12 | |
| 1/25/2010 | L 57-59 | @ | Winston Salem St | 7-17 | |
| 1/31/2010 | W 67-62 | Coppin St | 4-22 | ||
| 2/1/2010 | L 65-74 | Morgan St | 24-9 | ||
| 2/6/2010 | W 65-54 | Delaware St | 14-11 | ||
| 2/8/2010 | L 52-62 | UM Eastern Shore | 10-22 | ||
| 2/13/2010 | L 49-59 | @ | Howard | 5-25 | |
| 2/15/2010 | W 69-65 | @ | Hampton | 13-18 | |
| 2/17/2010 | W 87-69 | South Carolina St | 16-12 | ||
| 2/22/2010 | L 74-79 | Winston Salem St | 7-17 | ||
| 2/27/2010 | L 65-77 | @ | Coppin St | 4-22 | |
| 3/1/2010 | L 67-81 | @ | Morgan St | 24-9 | |
| 3/4/2010 | L 66-67 | Norfolk St | 11-18 | ||
| 3/6/2010 | W 65-54 | Delaware St | 14-11 | ||
| 3/9/2010 | W 65-55 | vs | Howard | 5-25 | Mid-Eastern |
| 3/10/2010 | L 57-84 | vs | Morgan St | 24-9 | Mid-Eastern |
| 9-22 | 304-317 |