| Date | Res | Opp | OW-OL | ||
| 11/13/2009 | W 67-43 | vs | Oregon St | 15-15 | Duel in the Desert |
| 11/14/2009 | L 59-66 | @ | Texas Tech | 17-14 | Duel in the Desert |
| 11/15/2009 | L 73-76 | vs | South Dakota | 17-9 | Duel in the Desert |
| 11/19/2009 | W 77-55 | UT Pan American | 5-26 | ||
| 11/29/2009 | L 58-73 | @ | Mississippi | 20-10 | |
| 12/6/2009 | L 76-83 | @ | Houston | 17-15 | |
| 12/20/2009 | L 76-85 | @ | Kent St | 21-9 | |
| 12/23/2009 | L 51-65 | @ | Monmouth | 11-20 | |
| 1/2/2010 | L 70-76 | @ | Texas | 23-9 | |
| 1/4/2010 | L 54-94 | @ | Florida St | 21-9 | |
| 1/9/2010 | W 64-59 | @ | Central Arkansas | 5-20 | |
| 1/13/2010 | W 68-59 | @ | Texas St | 11-14 | |
| 1/16/2010 | W 98-83 | Northwestern St | 7-17 | ||
| 1/20/2010 | W 81-64 | Lamar | 11-15 | ||
| 1/23/2010 | W 66-62 OT | @ | UT San Antonio | 15-9 | |
| 1/25/2010 | W 64-51 | @ | UT Pan American | 5-26 | |
| 1/30/2010 | L 58-70 | Sam Houston | 20-6 | ||
| 2/3/2010 | L 66-71 OT | @ | UT Arlington | 12-13 | |
| 2/6/2010 | W 71-46 | Nicholls St | 7-17 | ||
| 2/10/2010 | W 63-60 | Texas St | 11-14 | ||
| 2/13/2010 | L 74-90 | @ | Sam Houston | 20-6 | |
| 2/17/2010 | L 56-57 | UT San Antonio | 15-9 | ||
| 2/20/2010 | L 62-65 | @ | McNeese St | 6-20 | |
| 2/24/2010 | W 68-57 | SE Louisiana | 14-12 | ||
| 2/27/2010 | L 43-64 | @ | Stephen F. Austin | 18-9 | |
| 3/3/2010 | W 79-55 | @ | Lamar | 11-15 | |
| 3/6/2010 | W 71-46 | Nicholls St | 7-17 | ||
| 3/10/2010 | W 78-66 | vs | UT San Antonio | 15-9 | Southland |
| 3/11/2010 | L 53-60 | vs | Stephen F. Austin | 18-9 | Southland |
| 14-15 | 293-288 |