| Date | Res | Opp | OW-OL | ||
| 11/15/2009 | W 80-64 | Fairleigh Dickinson | 12-20 | CBE Classic | |
| 11/23/2009 | L 55-68 | vs | Pittsburgh | 23-8 | CBE Classic |
| 11/24/2009 | W 74-57 | vs | Iowa | 10-21 | CBE Classic |
| 11/28/2009 | W 69-54 | @ | Cleveland St | 15-15 | |
| 11/30/2009 | W 87-52 | Alcorn St | 1-29 | ||
| 12/3/2009 | W 74-43 | Texas Southern | 14-16 | ||
| 12/5/2009 | W 72-45 | SC Upstate | 7-22 | ||
| 12/9/2009 | W 73-52 | @ | UMKC | 10-17 | |
| 12/12/2009 | W 80-58 | TCU | 12-17 | ||
| 12/19/2009 | W 85-83 | Texas Tech | 18-13 | ||
| 12/21/2009 | W 69-57 | North Dakota St | 10-17 | ||
| 12/29/2009 | L 57-72 | @ | Illinois St | 21-8 | |
| 1/1/2010 | W 61-38 | at | Drake | 13-18 | |
| 1/3/2010 | W 81-69 | Bradley | 15-13 | ||
| 1/6/2010 | W 65-62 | @ | Missouri St | 21-9 | |
| 1/9/2010 | W 70-58 | Creighton | 15-14 | ||
| 1/13/2010 | W 84-73 | @ | Indiana St | 16-11 | |
| 1/16/2010 | L 56-57 | @ | Creighton | 15-14 | |
| 1/19/2010 | W 60-51 | Northern Iowa | 25-3 | ||
| 1/23/2010 | L 64-78 | @ | Drake | 13-18 | |
| 1/27/2010 | W 74-66 | Illinois St | 21-8 | ||
| 1/31/2010 | W 55-54 | @ | Southern Illinois | 14-14 | |
| 2/3/2010 | L 56-59 | @ | Northern Iowa | 25-3 | |
| 2/6/2010 | W 76-70 | Indiana St | 16-11 | ||
| 2/9/2010 | L 62-65 | @ | Evansville | 7-21 | |
| 2/14/2010 | W 66-64 | Missouri St | 21-9 | ||
| 2/17/2010 | W 76-70 OT | Evansville | 7-21 | ||
| 2/20/2010 | L 58-68 | @ | Utah St | 25-7 | Bracket Buster |
| 2/24/2010 | L 73-75 | @ | Bradley | 15-13 | |
| 2/27/2010 | W 76-55 | Southern Illinois | 14-14 | ||
| 3/6/2010 | W 76-70 | Indiana St | 16-11 | ||
| 3/7/2010 | L 52-67 | vs | Northern Iowa | 25-3 | Missouri Valley |
| 23-9 | 304-313 |