| Date | Res | Opp | OW-OL | ||
| 11/14/2008 | W 78-60 | Albany | 15-15 | ||
| 11/17/2008 | W 107-68 | Fordham | 3-24 | ||
| 11/19/2008 | W 77-62 | Niagara | 26-8 | ||
| 11/25/2008 | W 71-48 | Monmouth | 8-22 | ||
| 11/28/2008 | W 64-47 | vs | Towson | 12-21 | |
| 11/29/2008 | W 78-65 | vs | Rhode Island | 23-10 | |
| 12/2/2008 | W 69-47 | @ | Pennsylvania | 10-17 | |
| 12/4/2008 | W 93-57 | Houston Baptist | 4-24 | ||
| 12/9/2008 | L 58-67 | vs | Texas | 22-12 | |
| 12/11/2008 | W 59-56 | Saint Joseph's | 17-14 | ||
| 12/14/2008 | W 70-59 | @ | La Salle | 18-12 | |
| 12/22/2008 | W 78-68 | Navy | 19-10 | ||
| 12/29/2008 | W 62-45 | Temple | 22-11 | ||
| 1/1/2009 | L 72-79 | @ | Marquette | 24-8 | |
| 1/6/2009 | W 89-85 OT | @ | Seton Hall | 16-14 | |
| 1/10/2009 | L 60-61 | Louisville | 28-5 | ||
| 1/18/2009 | W 76-57 | St. John's | 16-17 | ||
| 1/21/2009 | L 83-89 | @ | Connecticut | 29-4 | |
| 1/24/2009 | W 70-61 | @ | South Florida | 9-21 | |
| 1/28/2009 | W 67-57 | Pittsburgh | 30-3 | ||
| 2/1/2009 | W 71-50 | Cincinnati | 17-13 | ||
| 2/4/2009 | W 94-91 | @ | Providence | 19-12 | |
| 2/7/2009 | W 102-85 | Syracuse | 27-7 | ||
| 2/10/2009 | W 102-84 | Marquette | 24-8 | ||
| 2/13/2009 | L 72-93 | @ | West Virginia | 22-12 | |
| 2/19/2009 | W 82-72 | Rutgers | 11-20 | ||
| 2/22/2009 | W 89-86 | @ | Syracuse | 27-7 | |
| 2/25/2009 | W 74-72 | @ | DePaul | 9-23 | |
| 2/28/2009 | L 54-56 | Georgetown | 15-15 | ||
| 3/2/2009 | W 77-60 | @ | Notre Dame | 20-13 | |
| 3/5/2009 | W 97-80 | Providence | 19-12 | ||
| 3/12/2009 | W 76-75 | vs | Marquette | 24-8 | Big East |
| 3/13/2009 | L 55-69 | vs | Louisville | 28-5 | Big East |
| 3/19/2009 | W 80-67 | vs | American | 24-7 | East |
| 3/21/2009 | W 89-69 | vs | UCLA | 25-8 | East |
| 9/26/2009 | W 77-54 | vs | Duke | 30-6 | East |
| 29-7 | 570-408 |