| Date | Res | Opp | OW-OL | ||
| 11/14/2008 | W 68-38 | Stetson | 11-16 | ||
| 11/18/2008 | W 76-51 | Tulane | 13-16 | ||
| 11/24/2008 | W 68-50 | vs | Saint Joseph's | 17-14 | |
| 11/25/2008 | L 80-81 | vs | Notre Dame | 19-14 | |
| 11/26/2008 | W 70-57 | vs | Oregon | 8-22 | |
| 11/30/2008 | W 77-56 | Rice | 10-21 | ||
| 12/4/2008 | W 68-64 | UCLA | 25-8 | ||
| 12/9/2008 | W 67-58 | vs | Villanova | 29-6 | |
| 12/13/2008 | W 81-73 | Texas St | 10-15 | ||
| 12/16/2008 | W 88-72 | Texas Southern | 7-24 | ||
| 12/20/2008 | L 63-67 | vs | Michigan St | 27-6 | |
| 12/23/2008 | W 74-69 | @ | Wisconsin | 19-12 | |
| 1/2/2009 | W 78-43 | Appalachian St | 12-17 | ||
| 1/6/2009 | L 61-67 | @ | Arkansas | 13-16 | |
| 1/10/2009 | W 75-67 | Iowa State | 14-16 | ||
| 1/12/2009 | L 63-78 | @ | Oklahoma | 28-4 | |
| 1/17/2009 | W 71-49 | @ | Texas Tech | 13-17 | |
| 1/24/2009 | W 67-58 | Texas A&M | 22-9 | ||
| 1/27/2009 | W 78-72 | @ | Baylor | 21-12 | |
| 1/31/2009 | L 81-85 OT | Kansas St | 20-11 | ||
| 2/4/2009 | L 65-69 | Missouri | 29-6 | ||
| 2/7/2009 | L 55-58 | @ | Nebraska | 17-13 | |
| 2/10/2009 | W 99-74 | Oklahoma St | 21-11 | ||
| 2/14/2009 | W 85-76 OT | @ | Colorado | 8-20 | |
| 2/16/2009 | L 66-81 | @ | Texas A&M | 22-9 | |
| 2/21/2009 | W 73-68 | Oklahoma | 28-4 | ||
| 2/25/2009 | W 87-81 | Texas Tech | 13-17 | ||
| 2/28/2009 | L 59-68 | @ | Oklahoma St | 21-11 | |
| 3/2/2009 | W 73-57 | Baylor | 21-12 | ||
| 3/7/2009 | L 73-83 | @ | Kansas | 26-7 | |
| 3/11/2009 | W 67-56 | vs | Colorado | 8-20 | Big 12 |
| 3/12/2009 | W 61-58 | vs | Kansas St | 20-11 | Big 12 |
| 3/13/2009 | L 70-76 | vs | Baylor | 21-12 | Big 12 |
| 3/19/2009 | W 76-62 | vs | Minnesota | 21-10 | East |
| 3/21/2009 | L 69-74 | vs | Duke | 29-7 | East |
| 23-12 | 489-350 |