| Date | Res | Opp | OW-OL | ||
| 11/14/2008 | W 86-63 | Fairleigh Dickinson | 7-22 | ||
| 11/17/2008 | W 82-52 | Miami-Ohio | 17-12 | ||
| 11/21/2008 | W 86-67 | Akron | 22-12 | ||
| 11/25/2008 | W 74-60 | Belmont | 20-12 | ||
| 11/28/2008 | W 80-67 | vs | Texas Tech | 13-18 | |
| 11/29/2008 | W 57-43 | vs | Washington St | 17-15 | |
| 12/3/2008 | W 78-51 | Duquesne | 21-12 | ||
| 12/6/2008 | W 80-51 | Vermont | 24-8 | ||
| 12/13/2008 | W 91-56 | UMBC | 14-16 | ||
| 12/17/2008 | W 79-66 | Siena | 27-7 | ||
| 12/21/2008 | W 56-48 | @ | Florida St | 25-9 | |
| 12/31/2008 | W 78-72 | @ | Rutgers | 11-20 | |
| 1/3/2009 | W 70-54 | @ | Georgetown | 16-14 | |
| 1/11/2009 | W 90-67 | St. John's | 16-17 | ||
| 1/14/2009 | W 75-62 | South Florida | 9-21 | ||
| 1/17/2009 | L 63-69 | @ | Louisville | 29-5 | |
| 1/19/2009 | W 78-60 | Syracuse | 27-8 | ||
| 1/25/2009 | W 79-67 | @ | West Virginia | 22-10 | |
| 1/28/2009 | L 57-67 | @ | Villanova | 28-7 | |
| 1/31/2009 | W 93-80 | Notre Dame | 20-13 | ||
| 2/2/2009 | W 92-72 | Robert Morris | 24-10 | ||
| 2/7/2009 | W 92-69 | @ | DePaul | 9-22 | |
| 2/9/2009 | W 70-59 | West Virginia | 22-10 | ||
| 2/14/2009 | W 85-69 | Cincinnati | 17-13 | ||
| 2/16/2009 | W 76-68 | @ | Connecticut | 30-2 | |
| 2/21/2009 | W 80-61 | DePaul | 9-22 | ||
| 2/24/2009 | L 73-81 | @ | Providence | 18-14 | |
| 2/28/2009 | W 89-78 | @ | Seton Hall | 16-14 | |
| 3/4/2009 | W 90-75 | Marquette | 25-9 | ||
| 3/7/2009 | W 70-60 | Connecticut | 30-2 | ||
| 3/12/2009 | L 60-74 | vs | West Virginia | 22-10 | Big East |
| 3/20/2009 | W 72-62 | vs | East Tenn St | 21-10 | East |
| 3/22/2009 | W 84-76 | vs | Oklahoma St | 22-11 | East |
| 9/26/2009 | W 60-55 | vs | Xavier | 27-7 | East |
| 30-4 | 594-370 |