| Date | Res | Opp | OW-OL | ||
| 11/14/2008 | W 71-43 | IPFW | 12-16 | ||
| 11/17/2008 | W 81-65 | Toledo | 6-24 | ||
| 11/20/2008 | W 75-71 | vs | Missouri | 30-5 | |
| 11/21/2008 | W 63-62 OT | vs | Virginia Tech | 19-14 | |
| 11/23/2008 | W 63-58 | vs | Memphis | 33-3 | |
| 11/29/2008 | W 60-53 | Miami-Ohio | 17-12 | ||
| 12/3/2008 | W 81-74 | Auburn | 23-11 | ||
| 12/10/2008 | W 78-56 | Ohio | 15-16 | ||
| 12/13/2008 | W 76-66 | @ | Cincinnati | 17-13 | |
| 12/20/2008 | L 64-82 | vs | Duke | 29-7 | |
| 12/23/2008 | L 65-74 | Butler | 24-6 | ||
| 12/31/2008 | W 78-57 | Robert Morris | 24-10 | ||
| 1/3/2009 | W 84-70 | @ | Virginia | 10-17 | |
| 1/8/2009 | W 70-44 | Saint Louis | 17-12 | ||
| 1/11/2009 | W 86-60 | @ | Fordham | 3-23 | |
| 1/15/2009 | W 67-65 | @ | Rhode Island | 23-10 | |
| 1/18/2009 | W 73-53 | La Salle | 18-12 | ||
| 1/21/2009 | W 84-64 | @ | St. Bonaventure | 15-14 | |
| 1/24/2009 | W 80-70 | @ | LSU | 27-7 | |
| 1/28/2009 | W 69-47 | Charlotte | 10-19 | ||
| 1/31/2009 | W 82-80 | Massachusetts | 11-17 | ||
| 2/5/2009 | W 83-74 | Temple | 21-11 | ||
| 2/7/2009 | L 68-72 | @ | Duquesne | 20-13 | |
| 2/11/2009 | L 58-71 | @ | Dayton | 26-7 | |
| 2/14/2009 | W 88-53 | Fordham | 3-23 | ||
| 2/19/2009 | L 60-65 | @ | Charlotte | 10-19 | |
| 2/22/2009 | W 71-53 | George Washington | 10-17 | ||
| 2/26/2009 | W 68-54 | @ | Saint Joseph's | 17-14 | |
| 3/5/2009 | W 76-59 | Dayton | 26-7 | ||
| 3/7/2009 | L 75-80 | @ | Richmond | 17-16 | |
| 3/12/2009 | W 66-47 | vs | Saint Louis | 17-12 | Atlantic 10 |
| 3/13/2009 | L 53-55 | vs | Temple | 21-11 | Atlantic 10 |
| 3/20/2009 | W 77-59 | vs | Portland | 18-13 | East |
| 3/22/2009 | W 60-49 | vs | Wisconsin | 19-12 | East |
| 9/26/2009 | L 55-60 | vs | Pittsburgh | 29-4 | East |
| 27-8 | 560-375 |