| 7 Nov | Jacksonville 44 | at | Duke 71 | vs ASUN | ||
| 11 Nov | SC Upstate 38 | at | Duke 84 | vs BSo | ||
| 15 Nov | Kansas 69 | vs | Duke 64 | Indianapolis, IN | vs B12 | |
| 18 Nov | Delaware 58 | at | Duke 92 | vs CAA | ||
| 21 Nov | Bellarmine 57 | at | Duke 74 | vs ASUN | ||
| 24 Nov | Duke 54 | vs | Oregon St 51 | Portland, OR | vs P12 | |
| 25 Nov | Duke 71 | vs | Xavier 64 | Portland, OR | vs BE | |
| 27 Nov | Purdue 75 | vs | Duke 56 | Portland, OR | vs B10 | |
| 30 Nov | Ohio St 72 | at | Duke 81 | vs B10 | ||
| 3 Dec | Boston College 59 | at | Duke 75 | |||
| 6 Dec | Duke 74 | vs | Iowa 62 | New York, NY | vs B10 | |
| 10 Dec | MD E Shore 55 | at | Duke 82 | vs MEAC | ||
| 20 Dec | Duke 70 | at | Wake Forest 81 | |||
| 31 Dec | Florida St 67 | at | Duke 86 | |||
| 4 Jan | Duke 60 | at | NC State 84 | |||
| 7 Jan | Duke 65 | at | Boston College 64 | |||
| 11 Jan | Pittsburgh 69 | at | Duke 77 | |||
| 14 Jan | Duke 64 | at | Clemson 72 | |||
| 21 Jan | Miami FL 66 | at | Duke 68 | |||
| 23 Jan | Duke 75 | at | Virginia Tech 78 | |||
| 28 Jan | Duke 86 | at | Georgia Tech 43 | |||
| 31 Jan | Wake Forest 73 | at | Duke 75 | |||
| 4 Feb | North Carolina 57 | at | Duke 63 | |||
| 6 Feb | Duke 59 | at | Miami FL 81 | |||
| 11 Feb | Duke 62 | at | Virginia 69 | OT | ||
| 14 Feb | Notre Dame 64 | at | Duke 68 | |||
| 18 Feb | Duke 77 | at | Syracuse 55 | |||
| 20 Feb | Louisville 62 | at | Duke 79 | |||
| 25 Feb | Virginia Tech 65 | at | Duke 81 | |||
| 28 Feb | NC State 67 | at | Duke 71 | |||
| 4 Mar | Duke 62 | at | North Carolina 57 | |||
| 9 Mar | Duke 96 | vs | Pittsburgh 69 | Greensboro, NC | ||
| 10 Mar | Duke 85 | vs | Miami FL 78 | Greensboro, NC | ||
| 11 Mar | Duke 59 | vs | Virginia 49 | Greensboro, NC | ||
| 16 Mar | Duke 74 | vs | Oral Roberts 51 | Orlando, FL | vs SL | |
| 18 Mar | Tennessee 65 | vs | Duke 52 | Orlando, FL | vs SEC |
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