| Date | Res | Opp | OW-OL | ||
| 11/15/2009 | W 82-60 | @ | SIU-Edwardsville | 3-23 | |
| 11/21/2009 | W 71-55 | North Florida | 13-17 | ||
| 11/23/2009 | W 69-65 | @ | UIC | 8-21 | |
| 11/27/2009 | W 79-66 | Norfolk St | 12-18 | Basketball Travelers Tournament | |
| 11/28/2009 | W 93-53 | SE Missouri St | 6-23 | Basketball Travelers Tournament | |
| 11/29/2009 | W 80-77 | St. Bonaventure | 14-14 | Basketball Travelers Tournament | |
| 12/5/2009 | W 75-62 | Central Michigan | 14-15 | ||
| 12/13/2009 | L 68-76 | Niagara | 17-15 | ||
| 12/16/2009 | L 57-75 | @ | Ohio | 19-15 | |
| 12/19/2009 | W 73-63 | @ | Utah | 14-15 | |
| 12/22/2009 | W 80-56 | Grambling St | 7-19 | ||
| 12/29/2009 | W 72-57 | Wichita St | 22-8 | ||
| 1/1/2010 | L 64-68 | at | Missouri St | 20-10 | |
| 1/3/2010 | W 68-61 | Southern Illinois | 13-15 | ||
| 1/6/2010 | W 82-63 | @ | Evansville | 8-20 | |
| 1/9/2010 | L 44-59 | Northern Iowa | 25-4 | ||
| 1/13/2010 | W 70-56 | Evansville | 8-20 | ||
| 1/17/2010 | L 59-69 | at | Drake | 13-17 | |
| 1/20/2010 | W 71-62 | Creighton | 16-13 | ||
| 1/23/2010 | L 80-81 OT | @ | Southern Illinois | 13-15 | |
| 1/27/2010 | L 66-74 | @ | Wichita St | 22-8 | |
| 1/30/2010 | W 66-47 | Bradley | 16-12 | ||
| 2/3/2010 | L 65-72 | @ | Indiana St | 15-13 | |
| 2/6/2010 | W 71-68 | Drake | 13-17 | ||
| 2/9/2010 | W 62-61 | @ | Bradley | 16-12 | |
| 2/13/2010 | W 67-63 | @ | Creighton | 16-13 | |
| 2/17/2010 | W 76-72 | Missouri St | 20-10 | ||
| 2/20/2010 | W 71-62 | Morehead St | 21-8 | Bracket Buster | |
| 2/24/2010 | W 75-58 | Indiana St | 15-13 | ||
| 2/27/2010 | L 55-61 | @ | Northern Iowa | 25-4 | |
| 3/6/2010 | W 71-68 | Drake | 13-17 | ||
| 22-9 | 296-315 |