| 7 Nov | UNT Dallas 57 | at | Grambling 82 | vs ND1 | ||
| 11 Nov | Colorado 74 | at | Grambling 83 | vs P12 | ||
| 18 Nov | Grambling 48 | at | Grand Canyon 81 | at WAC | ||
| 22 Nov | Grambling 49 | at | Arizona St 80 | at P12 | ||
| 25 Nov | Grambling 75 | at | UT San Antonio 55 | at CUSA | ||
| 27 Nov | Incarnate Word 63 | vs | Grambling 61 | San Antonio, TX | vs SLC | |
| 28 Nov | Grambling 73 | vs | Dartmouth 49 | San Antonio, TX | vs Ivy | |
| 3 Dec | Incarnate Word 39 | at | Grambling 72 | vs SLC | ||
| 9 Dec | Grambling 64 | at | Vanderbilt 62 | at SEC | ||
| 17 Dec | Grambling 48 | at | Virginia Tech 74 | at ACC | ||
| 19 Dec | Grambling 56 | at | Liberty 75 | at ASUN | ||
| 29 Dec | North American 42 | at | Grambling 101 | vs ND1 | ||
| 2 Jan | Grambling 60 | at | Prairie View 61 | |||
| 4 Jan | Grambling 85 | at | TX Southern 72 | |||
| 7 Jan | Bethune-Cookman 70 | at | Grambling 76 | |||
| 9 Jan | Florida A&M 57 | at | Grambling 62 | |||
| 14 Jan | Grambling 73 | at | Southern Univ 81 | |||
| 21 Jan | Grambling 65 | at | MS Valley St 61 | |||
| 23 Jan | Grambling 77 | at | Ark Pine Bluff 70 | |||
| 28 Jan | Jackson St 66 | at | Grambling 78 | |||
| 30 Jan | Alcorn St 63 | at | Grambling 60 | |||
| 4 Feb | Grambling 73 | at | Alabama St 60 | |||
| 6 Feb | Grambling 66 | at | Alabama A&M 60 | |||
| 11 Feb | TX Southern 46 | at | Grambling 65 | |||
| 13 Feb | Prairie View 64 | at | Grambling 68 | |||
| 18 Feb | Grambling 69 | vs | Southern Univ 64 | OT | Salt Lake City, UT | |
| 25 Feb | Grambling 69 | at | Florida A&M 55 | |||
| 27 Feb | Grambling 66 | at | Bethune-Cookman 54 | |||
| 2 Mar | Alabama A&M 48 | at | Grambling 60 | |||
| 4 Mar | Alabama St 49 | at | Grambling 69 | |||
| 8 Mar | Grambling 87 | vs | Bethune-Cookman 72 | Birmingham, AL | ||
| 10 Mar | Grambling 78 | vs | Jackson St 69 | Birmingham, AL | ||
| 11 Mar | TX Southern 61 | vs | Grambling 58 | Birmingham, AL |
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