| 8 Nov | Montana 63 | at | Duquesne 91 | vs BSC | ||
| 11 Nov | Duquesne 52 | at | Kentucky 77 | at SEC | ||
| 14 Nov | S Carolina St 71 | at | Duquesne 96 | vs MEAC | ||
| 18 Nov | Duquesne 85 | vs | Colgate 80 | Akron, OH | vs PL | |
| 21 Nov | North Florida 82 | at | Duquesne 83 | vs ASUN | ||
| 23 Nov | Alabama St 57 | at | Duquesne 75 | vs SWAC | ||
| 29 Nov | UC Santa Barbara 61 | at | Duquesne 72 | vs BWC | ||
| 3 Dec | Ball St 77 | at | Duquesne 78 | vs MAC | ||
| 8 Dec | Marshall 82 | at | Duquesne 71 | vs SBC | ||
| 11 Dec | New Mexico St 73 | at | Duquesne 60 | vs WAC | ||
| 14 Dec | DePaul 55 | at | Duquesne 66 | vs BE | ||
| 17 Dec | Indiana St 86 | at | Duquesne 92 | vs MVC | ||
| 21 Dec | Winthrop 57 | at | Duquesne 74 | vs BSo | ||
| 28 Dec | Duquesne 57 | at | Dayton 69 | |||
| 31 Dec | Rhode Island 61 | at | Duquesne 72 | |||
| 4 Jan | VCU 70 | at | Duquesne 79 | |||
| 7 Jan | Duquesne 73 | at | Richmond 75 | |||
| 11 Jan | Duquesne 92 | at | St Joseph's PA 80 | |||
| 18 Jan | Duquesne 56 | at | St Bonaventure 65 | |||
| 21 Jan | Fordham 65 | at | Duquesne 58 | |||
| 25 Jan | Loyola-Chicago 58 | at | Duquesne 72 | vs MVC | ||
| 28 Jan | Duquesne 79 | at | Massachusetts 87 | |||
| 4 Feb | Duquesne 93 | at | G Washington 67 | |||
| 8 Feb | George Mason 52 | at | Duquesne 75 | |||
| 11 Feb | St Bonaventure 54 | at | Duquesne 56 | |||
| 15 Feb | St Joseph's PA 62 | at | Duquesne 76 | |||
| 18 Feb | Duquesne 85 | at | St Louis 90 | |||
| 22 Feb | Duquesne 91 | at | La Salle 74 | |||
| 26 Feb | Davidson 71 | at | Duquesne 67 | |||
| 1 Mar | Massachusetts 79 | at | Duquesne 88 | |||
| 4 Mar | Duquesne 60 | at | Fordham 87 | |||
| 8 Mar | La Salle 81 | vs | Duquesne 70 | Brooklyn, NY | ||
| 19 Mar | Rice 84 | vs | Duquesne 78 | Daytona Beach, FL | vs CUSA |
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