| Date | Res | Opp | OW-OL | ||
| 11/8/2007 | W 71-55 | San Francisco | 9-20 | 2K Sports Classic | |
| 11/9/2007 | W 80-50 | Denver | 10-18 | 2K Sports Classic | |
| 11/12/2007 | W 99-59 | Alcorn St | 6-22 | ||
| 11/15/2007 | L 53-63 | vs | Memphis | 34-1 | 2K Sports Classic |
| 11/16/2007 | W 69-55 | vs | Gardner-Webb | 15-15 | 2K Sports Classic |
| 11/21/2007 | W 74-42 | Morehead St | 13-14 | ||
| 11/29/2007 | L 55-66 | @ | Southern California | 20-12 | Big 12-Pac 10 Challenge |
| 12/2/2007 | W 90-66 | @ | TCU | 13-15 | |
| 12/5/2007 | W 81-55 | Tulsa | 20-12 | ||
| 12/8/2007 | L 62-66 | Stephen F. Austin | 21-5 | ||
| 12/15/2007 | W 83-72 | Arkansas | 23-11 | ||
| 12/20/2007 | W 72-68 | vs | Gonzaga | 25-7 | |
| 12/29/2007 | W 88-82 2 OT | @ | West Virginia | 25-9 | |
| 1/5/2008 | W 61-49 | Rice | 3-26 | ||
| 1/7/2008 | W 81-57 | Mt St. Mary's | 19-14 | ||
| 1/12/2008 | L 82-84 | Kansas St | 19-12 | ||
| 1/14/2008 | L 55-85 | @ | Kansas | 31-3 | |
| 1/19/2008 | W 63-61 | Texas Tech | 15-13 | ||
| 1/26/2008 | W 77-71 | @ | Baylor | 20-9 | |
| 1/28/2008 | W 64-61 | Oklahoma St | 16-13 | ||
| 2/2/2008 | L 52-60 | @ | Texas A&M | 23-10 | |
| 2/6/2008 | L 54-64 | Texas | 26-6 | ||
| 2/9/2008 | L 58-72 | @ | Colorado | 10-19 | |
| 2/13/2008 | W 76-64 | Iowa State | 13-17 | ||
| 2/16/2008 | W 66-64 | @ | Texas Tech | 15-13 | |
| 2/19/2008 | W 92-91 OT | Baylor | 20-9 | ||
| 2/23/2008 | L 45-62 | @ | Texas | 26-6 | |
| 2/27/2008 | L 45-63 | @ | Nebraska | 18-12 | |
| 3/1/2008 | W 64-37 | Texas A&M | 23-10 | ||
| 3/5/2008 | W 68-56 | @ | Oklahoma St | 16-13 | |
| 3/8/2008 | W 75-66 | Missouri | 16-15 | ||
| 3/14/2008 | W 54-49 | vs | Colorado | 10-19 | Big 12 |
| 3/15/2008 | L 49-77 | vs | Texas | 26-6 | Big 12 |
| 3/21/2008 | W 72-64 | vs | Non-Div I | 87-114 | East |
| 3/23/2008 | L 48-78 | vs | Louisville | 25-8 | East |
| 23-12 | 575-452 |