| 7 Nov | Anderson SC 85 | at | Samford 109 | vs ND1 | ||
| 10 Nov | Spring Hill 61 | at | Samford 80 | vs ND1 | ||
| 12 Nov | Belhaven MS 38 | at | Samford 90 | vs ND1 | ||
| 17 Nov | Samford 84 | at | Alabama A&M 64 | at SWAC | ||
| 20 Nov | TX Southern 63 | at | Samford 78 | vs SWAC | ||
| 23 Nov | Valparaiso 49 | at | Samford 79 | vs MVC | ||
| 25 Nov | Louisiana Tech 79 | at | Samford 76 | vs CUSA | ||
| 27 Nov | TN Southern 84 | at | Samford 82 | vs ND1 | ||
| 30 Nov | Samford 98 | at | DePaul 103 | OT | at BE | |
| 4 Dec | Samford 77 | at | UCF 80 | OT | at AAC | |
| 10 Dec | Samford 58 | at | Louisiana 75 | at SBC | ||
| 17 Dec | Samford 61 | at | S Carolina St 62 | at MEAC | ||
| 21 Dec | Samford 56 | at | Belmont 79 | at MVC | ||
| 28 Dec | Mercer 69 | at | Samford 78 | |||
| 31 Dec | Samford 75 | at | Citadel 63 | |||
| 4 Jan | VMI 78 | at | Samford 87 | |||
| 7 Jan | Samford 70 | at | UNC Greensboro 68 | |||
| 11 Jan | Wofford 58 | at | Samford 83 | |||
| 14 Jan | Chattanooga 74 | at | Samford 75 | |||
| 18 Jan | Samford 69 | at | ETSU 59 | |||
| 21 Jan | W Carolina 65 | at | Samford 74 | |||
| 25 Jan | Samford 84 | at | Furman 91 | OT | ||
| 28 Jan | Samford 77 | at | Wofford 85 | |||
| 1 Feb | Samford 85 | at | W Carolina 77 | |||
| 4 Feb | ETSU 62 | at | Samford 73 | |||
| 8 Feb | Samford 70 | at | Mercer 69 | OT | ||
| 11 Feb | Citadel 70 | at | Samford 76 | |||
| 15 Feb | UNC Greensboro 71 | at | Samford 83 | |||
| 18 Feb | Samford 96 | at | VMI 61 | |||
| 22 Feb | Samford 75 | at | Chattanooga 70 | |||
| 25 Feb | Furman 93 | at | Samford 79 | |||
| 4 Mar | Chattanooga 85 | vs | Samford 82 | Asheville, NC |
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