| Date | Res | Opp | OW-OL | ||
| 11/13/2009 | L 57-75 | Stony Brook | 19-9 | ||
| 11/17/2009 | L 60-86 | @ | Marquette | 22-10 | |
| 11/20/2009 | L 53-70 | @ | Missouri St | 20-11 | Hispanic Fund Classic |
| 11/21/2009 | L 51-76 | vs | Eastern Michigan | 15-15 | Hispanic Fund Classic |
| 11/22/2009 | L 62-88 | vs | The Citadel | 13-15 | Hispanic Fund Classic |
| 11/28/2009 | W 65-58 | American | 11-20 | ||
| 12/5/2009 | W 53-50 | Delaware St | 13-12 | ||
| 12/9/2009 | W 80-72 | Navy | 14-16 | ||
| 12/19/2009 | L 46-87 | @ | Wright St | 18-13 | |
| 12/22/2009 | L 69-87 | @ | Northern Illinois | 9-21 | |
| 12/28/2009 | L 47-56 | @ | Ball State | 13-16 | |
| 1/2/2010 | L 60-74 | @ | Nebraska | 14-18 | |
| 1/4/2010 | L 54-88 | @ | Oklahoma | 13-17 | |
| 1/9/2010 | L 67-80 | South Carolina St | 14-14 | ||
| 1/11/2010 | L 70-75 | Winston Salem St | 8-17 | ||
| 1/16/2010 | W 67-51 | @ | Florida A&M | 7-21 | |
| 1/18/2010 | L 51-61 | @ | Bethune Cookman | 14-15 | |
| 1/23/2010 | W 70-62 | @ | Coppin St | 5-20 | |
| 1/25/2010 | L 54-91 | @ | Morgan St | 25-9 | |
| 1/30/2010 | W 67-66 | Howard | 7-24 | ||
| 2/1/2010 | L 65-79 | Hampton | 13-19 | ||
| 2/6/2010 | L 62-64 | @ | Norfolk St | 10-19 | |
| 2/8/2010 | W 62-52 | @ | North Carolina A&T | 9-21 | |
| 2/10/2010 | L 71-73 | @ | NCCU | 3-22 | |
| 2/13/2010 | L 71-80 | Florida A&M | 7-21 | ||
| 2/15/2010 | W 62-56 | Bethune Cookman | 14-15 | ||
| 2/20/2010 | W 66-52 | Coppin St | 5-20 | ||
| 2/22/2010 | L 61-65 | Morgan St | 25-9 | ||
| 2/27/2010 | W 68-66 OT | @ | Howard | 7-24 | |
| 3/4/2010 | L 37-57 | @ | Delaware St | 13-12 | |
| 3/6/2010 | L 62-64 | @ | Norfolk St | 10-19 | |
| 3/10/2010 | W 64-58 | vs | Coppin St | 5-20 | Mid-Eastern |
| 3/11/2010 | L 53-59 | vs | South Carolina St | 14-14 | Mid-Eastern |
| 11-22 | 309-394 |