| Date | Res | Opp | OW-OL | ||
| 11/13/2009 | W 68-56 | vs | UW Green Bay | 20-10 | Hispanic Fund Classic |
| 11/14/2009 | L 65-72 | @ | Kent St | 21-9 | Hispanic Fund Classic |
| 11/15/2009 | W 55-52 | vs | Samford | 8-19 | Hispanic Fund Classic |
| 11/17/2009 | W 87-62 | @ | Jacksonville St | 9-19 | |
| 11/21/2009 | W 72-56 | Georgia | 15-15 | ||
| 11/24/2009 | W 77-59 | Troy | 17-12 | ||
| 11/28/2009 | W 90-59 | Florida A&M | 8-21 | ||
| 12/2/2009 | W 65-64 | Middle Tenn St | 18-12 | ||
| 12/4/2009 | W 74-52 | East Tenn St | 18-13 | ||
| 12/16/2009 | W 64-47 | Cincinnati | 18-13 | ||
| 12/19/2009 | W 72-54 | @ | South Alabama | 14-15 | |
| 12/22/2009 | W 67-57 | Butler | 28-3 | ||
| 12/30/2009 | L 63-72 | @ | Virginia | 14-16 | |
| 1/2/2010 | W 73-72 | @ | Arkansas | 15-16 | |
| 1/6/2010 | W 76-68 | East Carolina | 7-20 | ||
| 1/9/2010 | W 58-49 | @ | Tulane | 7-21 | |
| 1/16/2010 | W 63-62 | @ | SMU | 13-15 | |
| 1/20/2010 | W 57-56 | Southern Miss | 15-11 | ||
| 1/23/2010 | W 61-59 | @ | Marshall | 19-8 | |
| 1/26/2010 | W 65-55 | Tulsa | 22-10 | ||
| 1/30/2010 | L 65-74 2 OT | UTEP | 25-6 | ||
| 2/3/2010 | L 75-85 | @ | Memphis | 20-10 | |
| 2/6/2010 | W 76-65 | @ | Rice | 7-21 | |
| 2/13/2010 | L 74-81 | Marshall | 19-8 | ||
| 2/17/2010 | W 59-54 | @ | Southern Miss | 15-11 | |
| 2/20/2010 | W 75-66 | Houston | 18-14 | ||
| 2/24/2010 | W 53-49 | @ | UCF | 13-16 | |
| 2/27/2010 | W 76-55 | Tulane | 7-21 | ||
| 3/3/2010 | L 65-70 | Memphis | 20-10 | ||
| 3/6/2010 | W 76-65 | @ | Rice | 7-21 | |
| 3/11/2010 | L 44-58 | vs | Southern Miss | 15-11 | Conference USA |
| 24-7 | 389-345 |