| Date | Res | Opp | OW-OL | ||
| 11/13/2009 | L 68-79 | @ | Appalachian St | 19-11 | |
| 11/15/2009 | L 71-76 | George Washington | 15-14 | ||
| 11/19/2009 | W 80-69 | vs | Penn State | 11-19 | C of Charleston Classic |
| 11/20/2009 | L 60-67 | vs | Miami (FL) | 18-13 | C of Charleston Classic |
| 11/22/2009 | L 66-74 | vs | South Florida | 18-12 | C of Charleston Classic |
| 11/24/2009 | W 115-95 | VMI | 6-19 | ||
| 11/29/2009 | W 86-56 | @ | Elon | 8-21 | |
| 12/5/2009 | L 52-57 | George Mason | 15-14 | ||
| 12/14/2009 | W 79-59 | Campbell | 18-10 | ||
| 12/16/2009 | L 69-80 | Wake Forest | 19-10 | ||
| 12/28/2009 | L 64-66 | @ | Richmond | 25-8 | |
| 1/2/2010 | L 57-91 | @ | VCU | 19-9 | |
| 1/4/2010 | W 62-61 | @ | William & Mary | 20-9 | |
| 1/6/2010 | W 57-50 | Georgia St | 10-19 | ||
| 1/9/2010 | L 46-59 | @ | George Mason | 15-14 | |
| 1/13/2010 | L 52-70 | Old Dominion | 24-9 | ||
| 1/16/2010 | L 56-79 | @ | Northeastern | 18-12 | |
| 1/18/2010 | L 67-69 | @ | Virginia | 14-16 | |
| 1/20/2010 | L 74-79 | @ | Georgia St | 10-19 | |
| 1/23/2010 | W 67-64 | James Madison | 12-18 | ||
| 1/27/2010 | L 54-93 | @ | Hofstra | 15-14 | |
| 1/30/2010 | L 53-58 | Towson | 8-19 | ||
| 2/3/2010 | L 60-73 | VCU | 19-9 | ||
| 2/8/2010 | L 62-69 | @ | Delaware | 6-23 | |
| 2/11/2010 | W 80-72 | @ | Towson | 8-19 | |
| 2/13/2010 | L 70-87 | Hofstra | 15-14 | ||
| 2/16/2010 | L 56-65 | Northeastern | 18-12 | ||
| 2/20/2010 | L 68-76 | @ | Radford | 16-12 | Bracket Buster |
| 2/24/2010 | W 75-69 | @ | Drexel | 17-14 | |
| 2/27/2010 | L 51-62 | William & Mary | 20-9 | ||
| 9-21 | 351-325 |