| Date | Res | Opp | OW-OL | ||
| 11/15/2007 | W 66-47 | William & Mary | 15-15 | ||
| 11/18/2007 | L 63-65 | New Orleans | 16-13 | ||
| 11/22/2007 | W 72-63 | vs | Rider | 23-9 | Old Spice Classic |
| 11/23/2007 | W 63-61 | vs | South Carolina | 14-17 | Old Spice Classic |
| 11/25/2007 | W 69-68 | vs | Villanova | 22-11 | Old Spice Classic |
| 11/28/2007 | L 58-81 | @ | Michigan St | 26-8 | Big Ten-ACC Challenge |
| 12/8/2007 | L 69-75 | @ | East Carolina | 8-18 | |
| 12/15/2007 | W 74-49 | South Carolina St | 12-19 | ||
| 12/21/2007 | W 66-65 | Davidson | 27-5 | ||
| 12/23/2007 | W 85-77 | Cincinnati | 13-17 | ||
| 12/27/2007 | W 79-73 | @ | Seton Hall | 17-14 | |
| 12/29/2007 | W 74-62 | Western Carolina | 9-20 | ||
| 1/5/2008 | W 50-43 | Presbyterian | 2-24 | ||
| 1/9/2008 | W 54-29 | NC Central | 3-22 | ||
| 1/12/2008 | L 62-93 | @ | North Carolina | 32-2 | |
| 1/15/2008 | L 54-70 | @ | Clemson | 21-10 | |
| 1/19/2008 | W 79-77 OT | Miami-Florida | 13-3 | ||
| 1/23/2008 | L 74-77 | Georgia Tech | 14-17 | ||
| 1/26/2008 | W 69-66 | @ | Florida St | 18-13 | |
| 1/31/2008 | L 72-92 | @ | Duke | 26-6 | |
| 2/3/2008 | W 67-65 | Wake Forest | 16-12 | ||
| 2/5/2008 | W 73-63 | Virginia Tech | 19-12 | ||
| 2/9/2008 | L 70-84 | @ | Maryland | 17-14 | |
| 2/14/2008 | L 65-82 | @ | Boston College | 13-17 | |
| 2/16/2008 | L 64-71 | Clemson | 21-10 | ||
| 2/20/2008 | L 70-84 | North Carolina | 32-2 | ||
| 2/24/2008 | L 60-78 | @ | Virginia | 14-15 | |
| 2/27/2008 | L 62-72 | Florida St | 18-13 | ||
| 3/1/2008 | L 86-87 | Duke | 26-6 | ||
| 3/8/2008 | L 67-78 | @ | Wake Forest | 16-12 | |
| 3/13/2008 | L 50-63 | vs | Non-Div I | 86-115 | ACC |
| 15-16 | 496-448 |